hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_05923.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CDC37 | Hsp90 co-chaperone Cdc37 (Hsp90 chaperone protein kinase-targeting subunit) (p50Cdc37) [Cleaved into: Hsp90 co-chaperone Cdc37, N-terminally processed] | 5 | UniProt NCBI |
| RPS6KB2 | Ribosomal protein S6 kinase beta-2 (S6K-beta-2) (S6K2) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 2) (P70S6K2) (p70-S6K 2) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14B) (p70 ribosomal S6 kinase beta) (S6K-beta) (p70 S6 kinase beta) (p70 S6K-beta) (p70 S6KB) (p70-beta) | 5 | UniProt NCBI |
| A6NIL8 | None | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04151 | 0.00662552789826 | 1.0 | CDC37 RPS6KB2 | PI3K-Akt signaling pathway |
| WP:WP3932 | 0.0130364105952 | 1.0 | CDC37 RPS6KB2 | Focal adhesion PI3K Akt mTOR signaling pathway |
| WP:WP4172 | 0.015571930313 | 1.0 | CDC37 RPS6KB2 | PI3K Akt signaling pathway |
| CORUM:5849 | 0.0499419797295 | 0.5 | CDC37 | HSP90-CDC37-LRRK2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CDC37 | RPS6KB2 | 0.956 | 0.34 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| A6NIL8 | CDC37 | 0.952 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| A6NIL8 | RPS6KB2 | 0.724 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes