hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05946.1
Confidence: Very High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
TPR | Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein) | 5 | UniProt   NCBI |
CTC1 | CST complex subunit CTC1 (Conserved telomere maintenance component 1) (HBV DNAPTP1-transactivated protein B) | 5 | UniProt   NCBI |
TEN1 | CST complex subunit TEN1 (Protein telomeric pathways with STN1 homolog) (Telomere length regulation protein TEN1 homolog) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  CORUM:6075 | 5.12628525639e-06 | 1.0 | CTC1 TEN1 | CST complex |
  REAC:R-HSA-174430 | 0.000133283416666 | 1.0 | CTC1 TEN1 | Telomere C-strand synthesis initiation |
  REAC:R-HSA-174411 | 0.000555347569442 | 1.0 | CTC1 TEN1 | Polymerase switching on the C-strand of the telomere |
  REAC:R-HSA-174417 | 0.000958615342944 | 1.0 | CTC1 TEN1 | Telomere C-strand (Lagging Strand) Synthesis |
  GO:1990879 | 0.00140460216025 | 1.0 | CTC1 TEN1 | CST complex |
  REAC:R-HSA-180786 | 0.00217867123396 | 1.0 | CTC1 TEN1 | Extension of Telomeres |
  REAC:R-HSA-157579 | 0.00845837067304 | 1.0 | CTC1 TEN1 | Telomere Maintenance |
  REAC:R-HSA-73886 | 0.0136718027788 | 1.0 | CTC1 TEN1 | Chromosome Maintenance |
  GO:0000782 | 0.0309012475255 | 1.0 | CTC1 TEN1 | telomere cap complex |
  GO:0000783 | 0.0309012475255 | 1.0 | CTC1 TEN1 | nuclear telomere cap complex |
  GO:0140445 | 0.0365196561665 | 1.0 | CTC1 TEN1 | chromosome, telomeric repeat region |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 TEN1 |  CTC1 | 0.993 |            | hein_WMM     bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     hein ()     bioplex3_HCT116     |
 TPR |  TEN1 | 0.987 |            | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
 TPR |  CTC1 | 0.06 | 0.216           | bioplex_WMM     bioplex3_WMM     WMM_only     |
Related Complexes