hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05955.1
Confidence: Very High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
SMG8 | Nonsense-mediated mRNA decay factor SMG8 (Amplified in breast cancer gene 2 protein) (Protein smg-8 homolog) | 5 | UniProt   NCBI |
SMG1 | Serine/threonine-protein kinase SMG1 (SMG-1) (hSMG-1) (EC 2.7.11.1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (Nonsense mediated mRNA decay-associated PI3K-related kinase SMG1) | 5 | UniProt   NCBI |
CIB3 | Calcium and integrin-binding family member 3 (Kinase-interacting protein 3) (KIP 3) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-975957 | 0.0436932800731 | 0.666666666667 | SMG1 SMG8 | Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
  REAC:R-HSA-927802 | 0.0436932800731 | 0.666666666667 | SMG1 SMG8 | Nonsense-Mediated Decay (NMD) |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 SMG8 |  CIB3 | 0.968 |            | bioplex3_WMM     bioplex3_HCT116     WMM_only     |
 SMG8 |  SMG1 | 0.966 | 0.14           | hein_WMM     bioplex_WMM     bioplex3_WMM     youn_WMM     WMM_only     |
Related Complexes