hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_05970.1
Complex Portal: CPX-22442
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| C1QBP | Complement component 1 Q subcomponent-binding protein, mitochondrial (ASF/SF2-associated protein p32) (Glycoprotein gC1qBP) (C1qBP) (Hyaluronan-binding protein 1) (Mitochondrial matrix protein p32) (gC1q-R protein) (p33) (SF2AP32) | 5 | UniProt NCBI |
| LBR | Delta(14)-sterol reductase LBR (Delta-14-SR) (EC 1.3.1.70) (3-beta-hydroxysterol Delta (14)-reductase) (C-14 sterol reductase) (C14SR) (Integral nuclear envelope inner membrane protein) (LMN2R) (Lamin-B receptor) (Sterol C14-reductase) | 5 | UniProt NCBI |
| RNASEH1 | Ribonuclease H1 (RNase H1) (EC 3.1.26.4) (Ribonuclease H type II) | 5 | UniProt NCBI |
| ZNF638 | Zinc finger protein 638 (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL-associated antigen se33-1) (Nuclear protein 220) (Zinc finger matrin-like protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0000590 | 0.0135443934278 | 0.5 | RNASEH1 C1QBP | Progressive external ophthalmoplegia |
| REAC:R-HSA-9013106 | 0.0212029570934 | 0.5 | C1QBP LBR | RHOC GTPase cycle |
| CORUM:4498 | 0.049938562206 | 0.25 | C1QBP | p32-CBF-DNA complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| C1QBP | LBR | 0.998 | 0.178 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt hein () bioplex3_HCT116 boldt_WMM | |
| C1QBP | RNASEH1 | 0.989 | 0.152 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| LBR | RNASEH1 | 0.966 | 0.1 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| ZNF638 | RNASEH1 | 0.962 | 0.121466666667 |
mutually_exclusive (O75596)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| ZNF638 | C1QBP | 0.904 | 0.116 | bioplex_WMM bioplex3_WMM WMM_only | |
| ZNF638 | LBR | 0.705 | 0.15 | bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM WMM_only |
Related Complexes