hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_05971.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SREBF2 | Sterol regulatory element-binding protein 2 (SREBP-2) (Class D basic helix-loop-helix protein 2) (bHLHd2) (Sterol regulatory element-binding transcription factor 2) [Cleaved into: Processed sterol regulatory element-binding protein 2 (Transcription factor SREBF2)] | 5 | UniProt NCBI |
| B4GALT7 | Beta-1,4-galactosyltransferase 7 (Beta-1,4-GalTase 7) (Beta4Gal-T7) (b4Gal-T7) (EC 2.4.1.-) (Proteoglycan UDP-galactose:beta-xylose beta1,4-galactosyltransferase I) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 7) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 7) (UDP-galactose:beta-xylose beta-1,4-galactosyltransferase) (XGPT) (XGalT-1) (Xylosylprotein 4-beta-galactosyltransferase) (EC 2.4.1.133) (Xylosylprotein beta-1,4-galactosyltransferase) | 5 | UniProt NCBI |
| LGR4 | Leucine-rich repeat-containing G-protein coupled receptor 4 (G-protein coupled receptor 48) | 5 | UniProt NCBI |
| RDH10 | Retinol dehydrogenase 10 (EC 1.1.1.300) (Short chain dehydrogenase/reductase family 16C member 4) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7514 | 0.049938562206 | 0.25 | SREBF2 | SCAP-SREBF2 complex |
| CORUM:7516 | 0.049938562206 | 0.25 | SREBF2 | PAQR3-SREBF2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| LGR4 | RDH10 | 0.974 | 0.096 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| LGR4 | SREBF2 | 0.959 | 0.072 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| LGR4 | B4GALT7 | 0.955 | 0.092 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
| SREBF2 | RDH10 | 0.434 | 0.102 | bioplex_WMM bioplex3_WMM WMM_only |
| SREBF2 | B4GALT7 | 0.159 | 0.108 | bioplex_WMM bioplex3_WMM WMM_only |
| RDH10 | B4GALT7 | 0.045 | 0.066 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes