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hu.MAP 3.0
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hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):
Enrichment (ex. cilium):
Protein (ex. Centrosomal protein):
Complex:
huMAP3_06010.1
Confidence:
Very High
?
Proteins
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Genename
Protein Name
Uniprot Annotation Score
Links
MVB12A
Multivesicular body subunit 12A (CIN85/CD2AP family-binding protein) (ESCRT-I complex subunit MVB12A) (Protein FAM125A)
5
UniProt
NCBI
MVB12B
Multivesicular body subunit 12B (ESCRT-I complex subunit MVB12B) (Protein FAM125B)
5
UniProt
NCBI
PDCD6IP
Programmed cell death 6-interacting protein (PDCD6-interacting protein) (ALG-2-interacting protein 1) (ALG-2-interacting protein X) (Hp95)
5
UniProt
NCBI
TSG101
Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101)
5
UniProt
NCBI
UMAD1
UBAP1-MVB12-associated (UMA)-domain containing protein 1 (RPA3 antisense RNA 1) (RPA3 opposite strand)
2
UniProt
NCBI
VPS28
Vacuolar protein sorting-associated protein 28 homolog (H-Vps28) (ESCRT-I complex subunit VPS28)
5
UniProt
NCBI
VPS37B
Vacuolar protein sorting-associated protein 37B (hVps37B) (ESCRT-I complex subunit VPS37B)
5
UniProt
NCBI
Showing 1 to 7 of 7 entries
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Enrichments
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Term ID
Corrected Pval
Fraction Complex Coverage
Proteins
Term Name
REAC:R-HSA-162588
2.96622887934e-14
0.857142857143
TSG101 VPS37B MVB12B PDCD6IP MVB12A VPS28
Budding and maturation of HIV virion
REAC:R-HSA-174495
1.46579079198e-12
0.714285714286
TSG101 VPS28 MVB12A VPS37B MVB12B
Synthesis And Processing Of GAG, GAGPOL Polyproteins
REAC:R-HSA-174490
1.46579079198e-12
0.714285714286
TSG101 VPS28 MVB12A VPS37B MVB12B
Membrane binding and targetting of GAG proteins
GO:0046755
2.61043832372e-12
0.857142857143
TSG101 VPS37B MVB12B PDCD6IP MVB12A VPS28
viral budding
REAC:R-HSA-175474
3.19735900054e-12
0.714285714286
TSG101 VPS28 MVB12A VPS37B MVB12B
Assembly Of The HIV Virion
GO:0036258
1.90309081662e-11
0.857142857143
TSG101 VPS37B MVB12B PDCD6IP MVB12A VPS28
multivesicular body assembly
GO:0036257
2.34212799259e-11
0.857142857143
TSG101 VPS37B MVB12B PDCD6IP MVB12A VPS28
multivesicular body organization
GO:0019068
2.34212799259e-11
0.857142857143
TSG101 VPS37B MVB12B PDCD6IP MVB12A VPS28
virion assembly
GO:0000813
4.76240601112e-11
0.714285714286
TSG101 VPS28 MVB12A VPS37B MVB12B
ESCRT I complex
REAC:R-HSA-917729
1.04147201904e-10
0.714285714286
TSG101 VPS28 MVB12A VPS37B MVB12B
Endosomal Sorting Complex Required For Transport (ESCRT)
Showing 1 to 10 of 67 entries
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Edges
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Protein 1
Protein 2
Score
?
ProteomeHD
?
Evidence
?
MVB12A
VPS28
1.0
0.308
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () Malo bioplex3_HCT116 fraction
TSG101
MVB12A
1.0
0.366
hein_WMM bioplex_WMM bioplex3_WMM hein () Malo fraction
VPS37B
TSG101
1.0
0.252
hein_WMM bioplex_WMM Guru bioplex3_WMM youn_WMM hein () Malo fraction
VPS37B
VPS28
1.0
0.534
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM youn_WMM hein () Malo bioplex3_HCT116 fraction
TSG101
VPS28
1.0
0.912
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM youn_WMM hein () Malo bioplex3_HCT116 gupta_WMM fraction
MVB12B
VPS28
0.999
0.094
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
PDCD6IP
MVB12A
0.997
0.118
hein_WMM bioplex_WMM bioplex3_WMM WMM_only
VPS37B
MVB12A
0.997
0.268
hein_WMM bioplex_WMM bioplex3_WMM Malo fraction
UMAD1
VPS28
0.996
0.172
hein_WMM bioplex3_HEK293 bioplex3_WMM hein ()
TSG101
UMAD1
0.988
0.154
hein_WMM bioplex3_WMM WMM_only
Showing 1 to 10 of 21 entries
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Related Complexes
Genename
Complexes
VPS37B
huMAP3_01514.1
huMAP3_06010.1
huMAP3_07951.1
huMAP3_09572.1
huMAP3_12917.1
huMAP3_13805.1
MVB12B
huMAP3_00501.1
huMAP3_04792.1
huMAP3_06010.1
huMAP3_06241.1
huMAP3_06316.1
huMAP3_07951.1
huMAP3_08364.1
huMAP3_09572.1
huMAP3_10226.1
huMAP3_12917.1
huMAP3_13805.1
PDCD6IP
huMAP3_01514.1
huMAP3_03988.1
huMAP3_06010.1
huMAP3_06089.1
huMAP3_06564.1
huMAP3_07951.1
huMAP3_08679.1
huMAP3_09572.1
huMAP3_10053.1
huMAP3_12409.1
huMAP3_12917.1
huMAP3_13805.1
TSG101
huMAP3_01514.1
huMAP3_06010.1
huMAP3_07951.1
huMAP3_08679.1
huMAP3_09572.1
huMAP3_10053.1
huMAP3_12917.1
huMAP3_13805.1
VPS28
huMAP3_04792.1
huMAP3_06010.1
huMAP3_06533.1
huMAP3_07951.1
huMAP3_09572.1
huMAP3_12917.1
huMAP3_13805.1
UMAD1
huMAP3_01514.1
huMAP3_03988.1
huMAP3_06010.1
huMAP3_06564.1
huMAP3_07951.1
huMAP3_08679.1
huMAP3_09572.1
huMAP3_10053.1
huMAP3_12917.1
huMAP3_13805.1
MVB12A
huMAP3_01514.1
huMAP3_06010.1
huMAP3_07951.1
huMAP3_09572.1
huMAP3_12917.1
huMAP3_13805.1