hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_06013.1
Complex Portal: CPX-21311
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CD3D | T-cell surface glycoprotein CD3 delta chain (T-cell receptor T3 delta chain) (CD antigen CD3d) | 5 | UniProt NCBI |
| OSGEPL1 | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (O-sialoglycoprotein endopeptidase-like protein 1) (OSGEP-like protein 1) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEPL1) (tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPL1) | 5 | UniProt NCBI |
| SPPL2A | Signal peptide peptidase-like 2A (SPP-like 2A) (SPPL2a) (EC 3.4.23.-) (Intramembrane protease 3) (IMP-3) (Presenilin-like protein 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0004315 | 0.0359423574679 | 0.666666666667 | CD3D SPPL2A | Decreased circulating IgG level |
| HP:0010702 | 0.0429026841472 | 0.666666666667 | CD3D SPPL2A | Increased circulating antibody level |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SPPL2A | CD3D | 0.986 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| CD3D | OSGEPL1 | 0.984 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| SPPL2A | OSGEPL1 | 0.25 | 0.056 | bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| CD3D | huMAP3_02405.1 huMAP3_06013.1 |
| OSGEPL1 | huMAP3_02405.1 huMAP3_06013.1 huMAP3_11767.1 huMAP3_13049.1 |
| SPPL2A | huMAP3_01968.1 huMAP3_02388.1 huMAP3_06013.1 huMAP3_10978.1 huMAP3_11349.1 huMAP3_11691.1 huMAP3_13458.1 huMAP3_14460.1 |