hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_06020.1

Complex Portal: CPX-15859

Confidence: Very High

Genename	Protein Name	Uniprot Annotation Score	Links
H4C1	Histone H4	5	UniProt NCBI
CDIN1	CDAN1-interacting nuclease 1 (Protein HH114)	5	UniProt NCBI
UBN2	Ubinuclein-2	3	UniProt NCBI
IPO4	Importin-4 (Imp4) (Importin-4b) (Imp4b) (Ran-binding protein 4) (RanBP4)	5	UniProt NCBI
ASF1A	Histone chaperone ASF1A (Anti-silencing function protein 1 homolog A) (hAsf1) (hAsf1a) (CCG1-interacting factor A) (CIA) (hCIA)	5	UniProt NCBI
NPAT	Protein NPAT (Nuclear protein of the ataxia telangiectasia mutated locus) (Nuclear protein of the ATM locus) (p220)	5	UniProt NCBI
NASP	Nuclear autoantigenic sperm protein (NASP)	5	UniProt NCBI
CDAN1	Codanin-1	5	UniProt NCBI
ASF1B	Histone chaperone ASF1B (Anti-silencing function protein 1 homolog B) (hAsf1) (hAsf1b) (CCG1-interacting factor A-II) (CIA-II) (hCIA-II)	5	UniProt NCBI
HAT1	Histone acetyltransferase type B catalytic subunit (EC 2.3.1.48) (Histone acetyltransferase 1)	5	UniProt NCBI
MMS22L	Protein MMS22-like (Methyl methanesulfonate-sensitivity protein 22-like)	5	UniProt NCBI
TONSL	Tonsoku-like protein (Inhibitor of kappa B-related protein) (I-kappa-B-related protein) (IkappaBR) (NF-kappa-B inhibitor-like protein 2) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2)	5	UniProt NCBI
UBN1	Ubinuclein-1 (HIRA-binding protein) (Protein VT4) (Ubiquitously expressed nuclear protein)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:1150	1.82045571662e-13	0.416666666667	IPO4 ASF1B HAT1 ASF1A NASP	Histone H3.3 complex
CORUM:1149	4.8526101193e-13	0.416666666667	IPO4 ASF1B HAT1 ASF1A NASP	Histone H3.1 complex
CORUM:6149	2.5725558439e-08	0.25	IPO4 ASF1A CDAN1	Codanin-1-Asf1-histone H3.1-histone H4-importin-4 complex, cytosolic
CORUM:2236	5.13798447177e-07	0.25	ASF1B ASF1A NASP	ASF1-histone containing complex
GO:0006334	0.000177247949379	0.416666666667	UBN1 ASF1B HAT1 ASF1A NASP	nucleosome assembly
CORUM:2235	0.000375413311943	0.166666666667	ASF1B ASF1A	ASF1-interacting protein complex
GO:0006335	0.00042234232358	0.25	ASF1B ASF1A NASP	DNA replication-dependent chromatin assembly
GO:0034728	0.000466610129895	0.416666666667	UBN1 ASF1B HAT1 ASF1A NASP	nucleosome organization
GO:0065004	0.00622029696174	0.416666666667	UBN1 ASF1B HAT1 ASF1A NASP	protein-DNA complex assembly
REAC:R-HSA-2559584	0.0175295706997	0.166666666667	ASF1A UBN1	Formation of Senescence-Associated Heterochromatin Foci (SAHF)
GO:0006325	0.034714509451	0.5	UBN1 HAT1 ASF1B CDAN1 NASP ASF1A	chromatin organization

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
UBN2	ASF1A	1.0	0.09
IPO4	ASF1A	0.999	0.05
IPO4	ASF1B	0.999	0.074
ASF1B	HAT1	0.999	0.422	structurally_consistent (dimer)
ASF1A	UBN1	0.999	0.07	structurally_consistent (dimer)
ASF1B	NASP	0.998		structurally_consistent (dimer)
MMS22L	H4C1	0.998	0.511970984007
H4C1	HAT1	0.998	0.347671230091	structurally_consistent (dimer)
ASF1A	CDAN1	0.997	0.114
UBN2	ASF1B	0.997	0.096
ASF1B	H4C1	0.997	0.322
ASF1A	H4C1	0.997	0.253392125046	structurally_consistent (dimer)
ASF1B	UBN1	0.997	0.036	structurally_consistent (dimer)
H4C1	NASP	0.997		structurally_consistent (dimer)
TONSL	H4C1	0.996	0.298537142857
ASF1A	HAT1	0.995	0.364	mixed_interface
CDIN1	ASF1A	0.994	0.114	structurally_consistent (dimer)
ASF1A	NASP	0.993		structurally_consistent (dimer)
ASF1A	ASF1B	0.991	0.136	mutually_exclusive (P49321)
CDAN1	ASF1B	0.991	0.088	structurally_consistent (dimer)
ASF1B	TONSL	0.989	0.15
NASP	HAT1	0.984		structurally_consistent (dimer)
ASF1A	TONSL	0.984	0.097
H4C1	NPAT	0.982	0.612
CDIN1	ASF1B	0.982	0.044	structurally_consistent (dimer)
UBN2	UBN1	0.972	0.094
HAT1	NPAT	0.969	0.158
IPO4	H4C1	0.956	0.441090909091
ASF1B	NPAT	0.952	0.104
ASF1B	MMS22L	0.95	0.132
TONSL	MMS22L	0.909	0.452
NASP	NPAT	0.832
CDIN1	CDAN1	0.802	0.098	mutually_exclusive (Q9NVP2)
TONSL	NASP	0.801
TONSL	HAT1	0.781	0.05
ASF1A	NPAT	0.717	0.19
UBN2	HAT1	0.699	0.144
IPO4	TONSL	0.656	0.052
CDAN1	UBN1	0.645	0.04	mutually_exclusive (Q9NVP2)
CDIN1	UBN1	0.634	0.122	mutually_exclusive (Q9NVP2)
UBN2	CDAN1	0.634	0.072
CDIN1	H4C1	0.624	0.316666666667
IPO4	HAT1	0.619	0.108
IPO4	NASP	0.618
UBN2	NASP	0.616
CDAN1	H4C1	0.607	0.450155774427
CDIN1	UBN2	0.549	0.092
UBN1	NASP	0.538		mutually_exclusive (Q9NVP2)
IPO4	NPAT	0.51	0.072
IPO4	UBN1	0.496	0.06
UBN2	H4C1	0.466	0.389844035015
TONSL	NPAT	0.46	0.088
CDIN1	HAT1	0.44	0.12
ASF1A	MMS22L	0.411	0.174
MMS22L	NASP	0.386
MMS22L	NPAT	0.375	0.106
MMS22L	HAT1	0.358	0.166
CDAN1	HAT1	0.354	0.104
CDIN1	NASP	0.312
IPO4	MMS22L	0.263	0.146
TONSL	UBN1	0.263	0.062
CDIN1	TONSL	0.234	0.082
CDAN1	TONSL	0.234	0.134
IPO4	CDAN1	0.194	0.104
CDAN1	MMS22L	0.187	0.194
CDIN1	MMS22L	0.187	0.126
CDAN1	NASP	0.183
UBN1	H4C1	0.182	0.556615384615
CDIN1	IPO4	0.181	0.07
UBN2	TONSL	0.18	0.112
UBN1	MMS22L	0.165	0.07
UBN1	HAT1	0.137	0.098	mutually_exclusive (Q9NVP2)
UBN2	MMS22L	0.131	0.084
UBN2	IPO4	0.116	0.066
UBN2	NPAT	0.076	0.158

Related Complexes

Genename	Complexes
H4C1	huMAP3_01440.1 huMAP3_05517.1 huMAP3_05966.1 huMAP3_06020.1 huMAP3_07824.1 huMAP3_08143.1 huMAP3_09048.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_10862.1 huMAP3_12711.1
CDIN1	huMAP3_00115.1 huMAP3_00724.1 huMAP3_06020.1 huMAP3_06779.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_11832.1 huMAP3_11834.1 huMAP3_12711.1 huMAP3_12963.1
UBN2	huMAP3_00115.1 huMAP3_00724.1 huMAP3_01912.1 huMAP3_05517.1 huMAP3_06020.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_11745.1 huMAP3_11834.1 huMAP3_12711.1 huMAP3_12963.1
IPO4	huMAP3_00115.1 huMAP3_00724.1 huMAP3_03330.1 huMAP3_05068.1 huMAP3_05517.1 huMAP3_06020.1 huMAP3_06779.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09575.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_10785.1 huMAP3_12711.1 huMAP3_14135.1 huMAP3_14456.1
ASF1A	huMAP3_00115.1 huMAP3_00724.1 huMAP3_05517.1 huMAP3_06020.1 huMAP3_06779.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_11834.1 huMAP3_12711.1 huMAP3_12963.1
NPAT	huMAP3_01440.1 huMAP3_06020.1 huMAP3_06779.1 huMAP3_07299.1 huMAP3_08143.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_12711.1 huMAP3_15128.1
NASP	huMAP3_01440.1 huMAP3_05517.1 huMAP3_05966.1 huMAP3_06020.1 huMAP3_08143.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_12711.1 huMAP3_12925.1
CDAN1	huMAP3_00115.1 huMAP3_00724.1 huMAP3_06020.1 huMAP3_06779.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_11834.1 huMAP3_12711.1 huMAP3_12963.1
ASF1B	huMAP3_00115.1 huMAP3_00724.1 huMAP3_05517.1 huMAP3_06020.1 huMAP3_06779.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_11834.1 huMAP3_12711.1 huMAP3_12963.1
HAT1	huMAP3_01440.1 huMAP3_06020.1 huMAP3_06779.1 huMAP3_07299.1 huMAP3_08143.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_12711.1 huMAP3_13482.1 huMAP3_15128.1
MMS22L	huMAP3_00545.1 huMAP3_02289.1 huMAP3_03836.1 huMAP3_06020.1 huMAP3_06779.1 huMAP3_07824.1 huMAP3_08143.1 huMAP3_09048.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_10862.1 huMAP3_12711.1 huMAP3_14306.1
TONSL	huMAP3_00115.1 huMAP3_05517.1 huMAP3_06020.1 huMAP3_06779.1 huMAP3_07824.1 huMAP3_08143.1 huMAP3_09466.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_10862.1 huMAP3_12711.1 huMAP3_14306.1
UBN1	huMAP3_00115.1 huMAP3_00724.1 huMAP3_01912.1 huMAP3_05517.1 huMAP3_06020.1 huMAP3_08143.1 huMAP3_09289.1 huMAP3_09859.1 huMAP3_10747.1 huMAP3_11834.1 huMAP3_12711.1 huMAP3_12963.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_06020.1

Complex Portal: CPX-15859