hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06045.1
Complex Portal: CPX-13432
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LDHC | L-lactate dehydrogenase C chain (LDH-C) (EC 1.1.1.27) (Cancer/testis antigen 32) (CT32) (LDH testis subunit) (LDH-X) | 5 | UniProt NCBI |
| LDHAL6A | L-lactate dehydrogenase A-like 6A (LDHA-like protein 6A) (EC 1.1.1.27) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00640 | 7.55949079301e-05 | 1.0 | LDHC LDHAL6A | Propanoate metabolism |
| KEGG:00620 | 0.000146800434109 | 1.0 | LDHC LDHAL6A | Pyruvate metabolism |
| KEGG:00270 | 0.00016825963378 | 1.0 | LDHC LDHAL6A | Cysteine and methionine metabolism |
| KEGG:00010 | 0.000307419292249 | 1.0 | LDHC LDHAL6A | Glycolysis / Gluconeogenesis |
| KEGG:05230 | 0.000359441594481 | 1.0 | LDHC LDHAL6A | Central carbon metabolism in cancer |
| KEGG:04922 | 0.000680516741066 | 1.0 | LDHC LDHAL6A | Glucagon signaling pathway |
| REAC:R-HSA-70268 | 0.000743311362176 | 1.0 | LDHC LDHAL6A | Pyruvate metabolism |
| KEGG:04066 | 0.00078862558789 | 1.0 | LDHC LDHAL6A | HIF-1 signaling pathway |
| REAC:R-HSA-71406 | 0.00226581808332 | 1.0 | LDHC LDHAL6A | Pyruvate metabolism and Citric Acid (TCA) cycle |
| GO:0004457 | 0.00468200720083 | 1.0 | LDHC LDHAL6A | lactate dehydrogenase activity |
| GO:0004459 | 0.00468200720083 | 1.0 | LDHC LDHAL6A | L-lactate dehydrogenase activity |
| GO:0006089 | 0.016855225923 | 1.0 | LDHC LDHAL6A | lactate metabolic process |
| REAC:R-HSA-1428517 | 0.0242575818332 | 1.0 | LDHC LDHAL6A | The citric acid (TCA) cycle and respiratory electron transport |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| LDHC | LDHAL6A | 0.974 |
mutually_exclusive (P00338)
structurally_consistent (dimer) |
bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes