hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06046.1
Complex Portal: CPX-14655
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PPL | Periplakin (190 kDa paraneoplastic pemphigus antigen) (195 kDa cornified envelope precursor protein) | 5 | UniProt NCBI |
| POF1B | Protein POF1B (Premature ovarian failure protein 1B) | 5 | UniProt NCBI |
| EPPK1 | Epiplakin (450 kDa epidermal antigen) | 5 | UniProt NCBI |
| PKP3 | Plakophilin-3 | 5 | UniProt NCBI |
| CALML3 | Calmodulin-like protein 3 (CaM-like protein) (CLP) (Calmodulin-related protein NB-1) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6809371 | 0.0333121022189 | 0.4 | PPL PKP3 | Formation of the cornified envelope |
| REAC:R-HSA-6805567 | 0.035336387757 | 0.4 | PPL PKP3 | Keratinization |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PPL | CALML3 | 0.992 | 0.296 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM treiber_WMM | |
| PPL | POF1B | 0.988 | 0.146 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM treiber_WMM | |
| EPPK1 | POF1B | 0.976 | 0.086 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM treiber_WMM | |
| EPPK1 | CALML3 | 0.973 | 0.378 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only boldt_WMM treiber_WMM | |
| CALML3 | PKP3 | 0.963 | 0.186 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM | |
| PPL | PKP3 | 0.963 | 0.208 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM | |
| POF1B | PKP3 | 0.961 | 0.234 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM | |
| CALML3 | POF1B | 0.961 | 0.182 | bioplex_WMM bioplex3_WMM boldt boldt_WMM treiber_WMM WMM_only | |
| EPPK1 | PKP3 | 0.954 | 0.142 | bioplex_WMM bioplex3_WMM WMM_only treiber_WMM | |
| EPPK1 | PPL | 0.932 | 0.202 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM treiber_WMM WMM_only |
Related Complexes