hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_06054.1
Complex Portal: CPX-23001
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HNRNPF | Heterogeneous nuclear ribonucleoprotein F (hnRNP F) (Nucleolin-like protein mcs94-1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein F, N-terminally processed] | 5 | UniProt NCBI |
| HNRNPH1 | Heterogeneous nuclear ribonucleoprotein H (hnRNP H) [Cleaved into: Heterogeneous nuclear ribonucleoprotein H, N-terminally processed] | 5 | UniProt NCBI |
| HNRNPH2 | Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed] | 5 | UniProt NCBI |
| TARDBP | TAR DNA-binding protein 43 (TDP-43) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1287 | 5.12628525639e-06 | 0.5 | HNRNPF HNRNPH1 | HNRPF-HNRPH1 complex |
| WP:WP3584 | 1.19258348573e-05 | 0.75 | TARDBP HNRNPF HNRNPH1 | MECP2 and associated Rett syndrome |
| CORUM:1288 | 1.53774525569e-05 | 0.5 | HNRNPF HNRNPH1 | DCS complex (PTBP1, PTBP2, HNRPH1, HNRPF) |
| HPA:0461423 | 6.07442962134e-05 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; eccrine glands[High] |
| HPA:0471493 | 0.000179279261827 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 2; vascular mural cells[High] |
| HPA:0461493 | 0.000216822640131 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; vascular mural cells[High] |
| HPA:0570783 | 0.000295104410163 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | testis; preleptotene spermatocytes[High] |
| HPA:0100123 | 0.000353909608049 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | cerebral cortex; glial cells[High] |
| HPA:0351183 | 0.000500129327524 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | pancreas; pancreatic endocrine cells[High] |
| HPA:0461422 | 0.000545946772372 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; eccrine glands[>=Medium] |
| HPA:0130203 | 0.000583676551598 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | colon; endothelial cells[High] |
| HPA:0461492 | 0.000583682740574 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; vascular mural cells[>=Medium] |
| HPA:0270353 | 0.000589800331864 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | kidney; cells in glomeruli[High] |
| HPA:0471492 | 0.000603183823445 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 2; vascular mural cells[>=Medium] |
| HPA:0130243 | 0.000617955723071 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | colon; peripheral nerve/ganglion[High] |
| HPA:0440343 | 0.000624346951201 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | skeletal muscle; myocytes[High] |
| HPA:0461413 | 0.000751937516271 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; cells in spinous layer[High] |
| HPA:0461463 | 0.000871906552014 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; langerhans cells[High] |
| CORUM:1332 | 0.000972395234625 | 0.5 | HNRNPH1 TARDBP | Large Drosha complex |
| HPA:0471491 | 0.00117915609053 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 2; vascular mural cells[>=Low] |
| HPA:0460673 | 0.00119405798802 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | skin 1; melanocytes[High] |
| HPA:0460183 | 0.00121019630726 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; cells in granular layer[High] |
| HPA:0461421 | 0.00121019630726 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; eccrine glands[>=Low] |
| HPA:0461491 | 0.00122591780127 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; vascular mural cells[>=Low] |
| HPA:0471413 | 0.00129015959597 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 2; cells in spinous layer[High] |
| HPA:0630223 | 0.00142872046453 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | cervix; squamous epithelial cells[High] |
| HPA:0471463 | 0.00156945497833 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 2; langerhans cells[High] |
| HPA:0080133 | 0.00179344174456 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | caudate; neuronal cells[High] |
| REAC:R-HSA-72163 | 0.00185188916926 | 0.75 | HNRNPH2 HNRNPF HNRNPH1 | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 0.002052480752 | 0.75 | HNRNPH2 HNRNPF HNRNPH1 | mRNA Splicing |
| HPA:0330223 | 0.00216624768844 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | oral mucosa; squamous epithelial cells[High] |
| HPA:0460203 | 0.00258915473683 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; endothelial cells[High] |
| HPA:0470203 | 0.00264136105546 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 2; endothelial cells[High] |
| REAC:R-HSA-6803529 | 0.00282403231951 | 0.5 | HNRNPF HNRNPH1 | FGFR2 alternative splicing |
| HPA:0250133 | 0.00301973097362 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | hippocampus; neuronal cells[High] |
| HPA:0500702 | 0.00377175717623 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | soft tissue 1; peripheral nerve[>=Medium] |
| HPA:0390053 | 0.00378413373792 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | prostate; glandular cells[High] |
| HPA:0170053 | 0.00383394482509 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | endometrium 2; glandular cells[High] |
| HPA:0470673 | 0.0039388821921 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 2; melanocytes[High] |
| HPA:0050053 | 0.00420993404371 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | breast; glandular cells[High] |
| HPA:0570782 | 0.0042638852969 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | testis; preleptotene spermatocytes[>=Medium] |
| HPA:0570813 | 0.00430468776878 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | testis; spermatogonia cells[High] |
| REAC:R-HSA-72203 | 0.00469213914253 | 0.75 | HNRNPH2 HNRNPF HNRNPH1 | Processing of Capped Intron-Containing Pre-mRNA |
| HPA:0461473 | 0.00485810604426 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; lymphocytes[High] |
| HPA:0040083 | 0.00486221437914 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | bone marrow; hematopoietic cells[High] |
| HPA:0461443 | 0.00538769796026 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; fibrohistiocytic cells[High] |
| HPA:0050012 | 0.00563747045143 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | breast; adipocytes[>=Medium] |
| HPA:0420053 | 0.00570460747845 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | salivary gland; glandular cells[High] |
| HPA:0510702 | 0.00573839997476 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | soft tissue 2; peripheral nerve[>=Medium] |
| HPA:0360053 | 0.00692082285696 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | parathyroid gland; glandular cells[High] |
| HPA:0471473 | 0.00777897918936 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 2; lymphocytes[High] |
| HPA:0471443 | 0.00816119252153 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 2; fibrohistiocytic cells[High] |
| HPA:0570781 | 0.0111257647437 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | testis; preleptotene spermatocytes[>=Low] |
| HPA:0570762 | 0.0115490191121 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | testis; pachytene spermatocytes[>=Medium] |
| HPA:0320103 | 0.0122213209343 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | nasopharynx; respiratory epithelial cells[High] |
| HPA:0170252 | 0.0122512019146 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | endometrium 2; cells in endometrial stroma[>=Medium] |
| HPA:0570802 | 0.0125530345908 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | testis; sertoli cells[>=Medium] |
| HPA:0180053 | 0.0132366733002 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | epididymis; glandular cells[High] |
| HPA:0060103 | 0.0132366733002 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | bronchus; respiratory epithelial cells[High] |
| HPA:0100133 | 0.0134599376677 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | cerebral cortex; neuronal cells[High] |
| HPA:0460182 | 0.0136756650941 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; cells in granular layer[>=Medium] |
| HPA:0470182 | 0.0137538378506 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 2; cells in granular layer[>=Medium] |
| HPA:0030053 | 0.014482811552 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | appendix; glandular cells[High] |
| HPA:0590053 | 0.0145848028326 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | thyroid gland; glandular cells[High] |
| HPA:0570803 | 0.0146332934345 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | testis; sertoli cells[High] |
| CORUM:1181 | 0.0148970606176 | 0.5 | HNRNPF HNRNPH1 | C complex spliceosome |
| REAC:R-HSA-5654738 | 0.0151515389193 | 0.5 | HNRNPF HNRNPH1 | Signaling by FGFR2 |
| HPA:0461472 | 0.015549093194 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; lymphocytes[>=Medium] |
| HPA:0461462 | 0.0163259099541 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; langerhans cells[>=Medium] |
| HPA:0350473 | 0.0165893993359 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | pancreas; exocrine glandular cells[High] |
| HPA:0460202 | 0.0169474947772 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; endothelial cells[>=Medium] |
| HPA:0461412 | 0.017037547013 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; cells in spinous layer[>=Medium] |
| HPA:0490693 | 0.017127914433 | 0.75 | HNRNPH2 HNRNPF HNRNPH1 | smooth muscle; smooth muscle cells[High] |
| HPA:0250122 | 0.0174698944833 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | hippocampus; glial cells[>=Medium] |
| WP:WP411 | 0.0186440023495 | 0.5 | HNRNPH1 HNRNPH2 | mRNA processing |
| REAC:R-HSA-190236 | 0.019281632575 | 0.5 | HNRNPF HNRNPH1 | Signaling by FGFR |
| GO:0008380 | 0.0193524071449 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | RNA splicing |
| HPA:0610833 | 0.0196320462024 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | urinary bladder; urothelial cells[High] |
| HPA:0340462 | 0.0206302734533 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | ovary; ovarian stroma cells[>=Medium] |
| HPA:0470202 | 0.0206978936317 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 2; endothelial cells[>=Medium] |
| HPA:0461392 | 0.0214240997702 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; cells in basal layer[>=Medium] |
| HPA:0471472 | 0.0218465167628 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 2; lymphocytes[>=Medium] |
| HPA:0470672 | 0.0219529719185 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 2; melanocytes[>=Medium] |
| HPA:0270363 | 0.0232681464336 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | kidney; cells in tubules[High] |
| HPA:0471462 | 0.0233681465302 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 2; langerhans cells[>=Medium] |
| HPA:0570771 | 0.0241544629227 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | testis; peritubular cells[>=Low] |
| HPA:0471412 | 0.025307719873 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 2; cells in spinous layer[>=Medium] |
| HPA:0461442 | 0.0272274003475 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; fibrohistiocytic cells[>=Medium] |
| HPA:0570761 | 0.0273327385677 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | testis; pachytene spermatocytes[>=Low] |
| HPA:0010012 | 0.0275517827791 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | adipose tissue; adipocytes[>=Medium] |
| HPA:0460181 | 0.0284745500846 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; cells in granular layer[>=Low] |
| HPA:0160252 | 0.0287234436749 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | endometrium 1; cells in endometrial stroma[>=Medium] |
| HPA:0470181 | 0.0287284084928 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 2; cells in granular layer[>=Low] |
| HPA:0461471 | 0.0289837526614 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; lymphocytes[>=Low] |
| HPA:0461453 | 0.0292462264975 | 0.5 | HNRNPH2 TARDBP | skin 1; hair follicles[High] |
| HPA:0090183 | 0.0296286402726 | 0.75 | TARDBP HNRNPF HNRNPH1 | cerebellum; cells in granular layer[High] |
| HPA:0461461 | 0.0306799890508 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; langerhans cells[>=Low] |
| HPA:0020053 | 0.0309381158894 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | adrenal gland; glandular cells[High] |
| HPA:0080122 | 0.0312387757321 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | caudate; glial cells[>=Medium] |
| HPA:0470671 | 0.0317556027822 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 2; melanocytes[>=Low] |
| HPA:0471392 | 0.0346964580744 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 2; cells in basal layer[>=Medium] |
| HPA:0461411 | 0.0364546459466 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; cells in spinous layer[>=Low] |
| HPA:0570812 | 0.0387789758455 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | testis; spermatogonia cells[>=Medium] |
| HPA:0471461 | 0.0392002139957 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 2; langerhans cells[>=Low] |
| HPA:0550053 | 0.0399271079825 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | stomach 2; glandular cells[High] |
| HPA:0130053 | 0.0399997027243 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | colon; glandular cells[High] |
| HPA:0540053 | 0.0408047952341 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | stomach 1; glandular cells[High] |
| HPA:0471471 | 0.0414271565288 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 2; lymphocytes[>=Low] |
| HPA:0570801 | 0.0417718681023 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | testis; sertoli cells[>=Low] |
| HPA:0471442 | 0.0454353332194 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 2; fibrohistiocytic cells[>=Medium] |
| HPA:0460201 | 0.0471778151727 | 0.75 | TARDBP HNRNPH1 HNRNPH2 | skin 1; endothelial cells[>=Low] |
| HPA:0480053 | 0.048862114603 | 1.0 | HNRNPH2 TARDBP HNRNPF HNRNPH1 | small intestine; glandular cells[High] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| HNRNPF | HNRNPH1 | 0.996 | 0.93 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () gupta_WMM fraction boldt_WMM treiber_WMM | |
| HNRNPH1 | HNRNPH2 | 0.992 | 0.626 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM | |
| HNRNPF | TARDBP | 0.986 | 0.972 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () gupta_WMM fraction boldt_WMM treiber_WMM | |
| HNRNPF | HNRNPH2 | 0.986 | 0.576 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 gupta_WMM boldt_WMM treiber_WMM | |
| TARDBP | HNRNPH2 | 0.75 | 0.468 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM fraction treiber_WMM | |
| TARDBP | HNRNPH1 | 0.275 | 0.96 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
Related Complexes