hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_06057.1
Complex Portal: CPX-21795
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HIF1A | Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8) | 5 | UniProt NCBI |
| MYH3 | Myosin-3 (Muscle embryonic myosin heavy chain) (Myosin heavy chain 3) (Myosin heavy chain, fast skeletal muscle, embryonic) (SMHCE) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP3593 | 0.0272601008896 | 1.0 | HIF1A | MicroRNA for targeting cancer growth and vascularization in glioblastoma |
| WP:WP3672 | 0.0272601008896 | 1.0 | HIF1A | lncRNA mediated mechanisms of therapeutic resistance |
| WP:WP2456 | 0.0363468011862 | 1.0 | HIF1A | HIF1A and PPARG regulation of glycolysis |
| WP:WP3630 | 0.0454335014827 | 1.0 | HIF1A | NAD metabolism sirtuins and aging |
| CORUM:5382 | 0.0499436884912 | 1.0 | HIF1A | ARNT-HIF1A complex |
| CORUM:7273 | 0.0499436884912 | 1.0 | HIF1A | ARNTL-HIF1A complex |
| REAC:R-HSA-8849473 | 0.0499436884912 | 1.0 | HIF1A | PTK6 Expression |
| WP:WP5192 | 0.049976851631 | 1.0 | HIF1A | Modulation of PI3K Akt mTOR signaling by bioactive sphingolipids |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| HIF1A | MYH3 | 0.984 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| HIF1A | huMAP3_06057.1 huMAP3_09076.1 huMAP3_10799.1 huMAP3_14050.1 huMAP3_14138.1 huMAP3_14853.1 |
| MYH3 | huMAP3_06057.1 huMAP3_08441.1 huMAP3_09076.1 huMAP3_10799.1 huMAP3_14138.1 |