hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_06070.1

Confidence: Very High

Genename	Protein Name	Uniprot Annotation Score	Links
SRSF12	Serine/arginine-rich splicing factor 12 (35 kDa SR repressor protein) (SRrp35) (Splicing factor, arginine/serine-rich 13B) (Splicing factor, arginine/serine-rich 19)	5	UniProt NCBI
ETF1	Eukaryotic peptide chain release factor subunit 1 (Eukaryotic release factor 1) (eRF1) (Protein Cl1) (TB3-1)	5	UniProt NCBI
MKRN2	E3 ubiquitin-protein ligase makorin-2 (EC 2.3.2.27) (RING finger protein 62) (RING-type E3 ubiquitin transferase makorin-2)	5	UniProt NCBI
GSPT2	Eukaryotic peptide chain release factor GTP-binding subunit ERF3B (Eukaryotic peptide chain release factor subunit 3b) (eRF3b) (EC 3.6.5.-) (G1 to S phase transition protein 2 homolog)	5	UniProt NCBI
PABPC1L	Polyadenylate-binding protein 1-like	3	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
KEGG:03015	0.000112348611335	0.6	GSPT2 ETF1 PABPC1L	mRNA surveillance pathway
WP:WP107	0.00687274586933	0.4	GSPT2 ETF1	Translation factors
GO:0018444	0.0140440992017	0.4	GSPT2 ETF1	translation release factor complex
CORUM:809	0.0498708842806	0.2	ETF1	eRF1-eRF3-GTP-Mg(2+) complex

Protein 1	Protein 2	Score	ProteomeHD	Evidence
GSPT2	ETF1	0.987	0.686	youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM
MKRN2	GSPT2	0.983	0.168	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116
GSPT2	SRSF12	0.962	0.08	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
MKRN2	SRSF12	0.855	0.094	bioplex_WMM bioplex3_WMM WMM_only
MKRN2	ETF1	0.025	0.13	youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
ETF1	SRSF12	0.004	0.064	bioplex_WMM bioplex3_WMM WMM_only

Related Complexes

Genename	Complexes
SRSF12	huMAP3_02684.1 huMAP3_03519.1 huMAP3_05378.1 huMAP3_06070.1 huMAP3_07724.1 huMAP3_08614.1 huMAP3_08829.1 huMAP3_09490.1 huMAP3_09587.1 huMAP3_09621.1 huMAP3_10564.1 huMAP3_10628.1 huMAP3_11073.1
ETF1	huMAP3_00990.1 huMAP3_03127.1 huMAP3_03894.1 huMAP3_04700.1 huMAP3_05833.1 huMAP3_05874.1 huMAP3_05899.1 huMAP3_06070.1 huMAP3_07661.1 huMAP3_10114.1 huMAP3_10349.1 huMAP3_10628.1 huMAP3_10914.1 huMAP3_11148.1 huMAP3_14442.1
MKRN2	huMAP3_00714.1 huMAP3_00797.1 huMAP3_03127.1 huMAP3_03962.1 huMAP3_05252.1 huMAP3_05293.1 huMAP3_05560.1 huMAP3_05705.1 huMAP3_05745.1 huMAP3_05874.1 huMAP3_05899.1 huMAP3_06070.1 huMAP3_07375.1 huMAP3_07661.1 huMAP3_07973.1 huMAP3_08105.1 huMAP3_09142.1 huMAP3_09186.1 huMAP3_09376.1 huMAP3_09706.1 huMAP3_10114.1 huMAP3_10625.1 huMAP3_10628.1 huMAP3_11047.1 huMAP3_11073.1 huMAP3_11148.1
GSPT2	huMAP3_00797.1 huMAP3_03127.1 huMAP3_04700.1 huMAP3_05252.1 huMAP3_05293.1 huMAP3_05745.1 huMAP3_05874.1 huMAP3_05899.1 huMAP3_06070.1 huMAP3_06975.1 huMAP3_07661.1 huMAP3_07893.1 huMAP3_08748.1 huMAP3_09142.1 huMAP3_09186.1 huMAP3_09376.1 huMAP3_10114.1 huMAP3_10625.1 huMAP3_10628.1 huMAP3_11047.1 huMAP3_11073.1 huMAP3_11148.1 huMAP3_14192.1
PABPC1L	huMAP3_00714.1 huMAP3_00797.1 huMAP3_01334.1 huMAP3_03127.1 huMAP3_03962.1 huMAP3_05293.1 huMAP3_05560.1 huMAP3_05705.1 huMAP3_05745.1 huMAP3_05874.1 huMAP3_05899.1 huMAP3_06070.1 huMAP3_07375.1 huMAP3_07661.1 huMAP3_07893.1 huMAP3_07973.1 huMAP3_08105.1 huMAP3_09142.1 huMAP3_09186.1 huMAP3_09376.1 huMAP3_09706.1 huMAP3_10114.1 huMAP3_10625.1 huMAP3_10628.1 huMAP3_11047.1 huMAP3_11073.1 huMAP3_11148.1