hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_06074.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| COA8 | Cytochrome c oxidase assembly factor 8 (COA8) (Apoptogenic protein 1, mitochondrial) (APOP-1) | 5 | UniProt NCBI |
| SUOX | Sulfite oxidase, mitochondrial (EC 1.8.3.1) | 5 | UniProt NCBI |
| COX10 | Protoheme IX farnesyltransferase, mitochondrial (EC 2.5.1.141) (Heme O synthase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0001942 | 0.000387580252117 | 1.0 | COA8 SUOX COX10 | Metabolic acidosis |
| HP:0003688 | 0.00410807097178 | 0.666666666667 | COA8 COX10 | Cytochrome C oxidase-negative muscle fibers |
| HP:0001941 | 0.00651157857729 | 1.0 | COA8 SUOX COX10 | Acidosis |
| HP:0004360 | 0.00779492747058 | 1.0 | COA8 SUOX COX10 | Abnormality of acid-base homeostasis |
| WP:WP5030 | 0.0248274760036 | 0.333333333333 | SUOX | Ethylmalonic encephalopathy |
| HP:0001290 | 0.0304011063756 | 1.0 | COA8 SUOX COX10 | Generalized hypotonia |
| HP:0003800 | 0.0398445800112 | 0.666666666667 | COA8 COX10 | Muscle abnormality related to mitochondrial dysfunction |
| WP:WP4507 | 0.0496447587094 | 0.333333333333 | SUOX | Molybdenum cofactor Moco biosynthesis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| COA8 | COX10 | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SUOX | COX10 | 0.992 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SUOX | COA8 | 0.768 | bioplex3_WMM WMM_only |
Related Complexes