hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06095.1
Complex Portal: CPX-14529
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HK2 | Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II) (Hexokinase-B) (Muscle form hexokinase) | 5 | UniProt NCBI |
| NUBP2 | Cytosolic Fe-S cluster assembly factor NUBP2 (Nucleotide-binding protein 2) (NBP 2) | 5 | UniProt NCBI |
| GART | Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) (Glycinamide ribonucleotide synthetase) (GARS) (Phosphoribosylglycinamide synthetase); Phosphoribosylformylglycinamidine cyclo-ligase (EC 6.3.3.1) (AIR synthase) (AIRS) (Phosphoribosyl-aminoimidazole synthetase); Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) (5'-phosphoribosylglycinamide transformylase) (GAR transformylase) (GART)] | 5 | UniProt NCBI |
| SDF4 | 45 kDa calcium-binding protein (Cab45) (Stromal cell-derived factor 4) (SDF-4) | 5 | UniProt NCBI |
| NUBP1 | Cytosolic Fe-S cluster assembly factor NUBP1 (Nucleotide-binding protein 1) (NBP 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5152 | 0.000103023242897 | 0.666666666667 | NUBP2 NUBP1 | Iron sulfur cluster biogenesis |
| REAC:R-HSA-2564830 | 0.000531572756485 | 0.666666666667 | NUBP2 NUBP1 | Cytosolic iron-sulfur cluster assembly |
| KEGG:00524 | 0.0278821167741 | 0.333333333333 | HK2 | Neomycin, kanamycin and gentamicin biosynthesis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| NUBP2 | NUBP1 | 0.983 | 0.572 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| GART | NUBP2 | 0.97 | 0.11 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM WMM_only | |
| NUBP2 | HK2 | 0.962 | 0.04 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| HK2 | SDF4 | 0.956 | 0.032 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM | |
| NUBP2 | SDF4 | 0.955 | 0.05 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only | |
| GART | SDF4 | 0.944 | 0.104 | bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM WMM_only | |
| GART | HK2 | 0.554 | 0.374 | bioplex_WMM bioplex3_WMM boldt fraction boldt_WMM treiber_WMM | |
| GART | NUBP1 | 0.048 | 0.066 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| SDF4 | NUBP1 | 0.044 | 0.01 | bioplex_WMM bioplex3_WMM WMM_only | |
| HK2 | NUBP1 | 0.018 | 0.02 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes