hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06162.1
Complex Portal: CPX-16062
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CALHM4 | Calcium homeostasis modulator protein 4 (Protein FAM26D) | 3 | UniProt NCBI |
| CRYBG1 | Beta/gamma crystallin domain-containing protein 1 (Absent in melanoma 1 protein) | 4 | UniProt NCBI |
| IL31RA | Interleukin-31 receptor subunit alpha (IL-31 receptor subunit alpha) (IL-31R subunit alpha) (IL-31R-alpha) (IL-31RA) (Cytokine receptor-like 3) (GLM-R) (hGLM-R) (Gp130-like monocyte receptor) (Gp130-like receptor) (ZcytoR17) | 5 | UniProt NCBI |
| CSGALNACT1 | Chondroitin sulfate N-acetylgalactosaminyltransferase 1 (CsGalNAcT-1) (EC 2.4.1.174) (Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1) (Beta4GalNAcT-1) | 5 | UniProt NCBI |
| SELENBP1 | Methanethiol oxidase (MTO) (EC 1.8.3.4) (56 kDa selenium-binding protein) (SBP56) (SP56) (Selenium-binding protein 1) | 5 | UniProt NCBI |
| PLCD1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-1) (Phospholipase C-III) (PLC-III) (Phospholipase C-delta-1) (PLC-delta-1) | 5 | UniProt NCBI |
| HEPHL1 | Ferroxidase HEPHL1 (EC 1.16.3.1) (Hephaestin-like protein 1) | 5 | UniProt NCBI |
| OR51E2 | Olfactory receptor 51E2 (HPRAJ) (Olfactory receptor OR11-16) (Prostate-specific G-protein coupled receptor) | 5 | UniProt NCBI |
| LYG2 | Lysozyme g-like protein 2 (EC 3.2.1.-) | 4 | UniProt NCBI |
| DUSP14 | Dual specificity protein phosphatase 14 (EC 3.1.3.16) (EC 3.1.3.48) (MKP-1-like protein tyrosine phosphatase) (MKP-L) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6) | 5 | UniProt NCBI |
| DHRS12 | Dehydrogenase/reductase SDR family member 12 (EC 1.1.-.-) (Short-chain dehydrogenase/reductase family 40C member 1) (Protein SDR40C1) | 3 | UniProt NCBI |
| DSG4 | Desmoglein-4 (Cadherin family member 13) | 5 | UniProt NCBI |
| S100A3 | Protein S100-A3 (Protein S-100E) (S100 calcium-binding protein A3) | 5 | UniProt NCBI |
| NEU2 | Sialidase-2 (EC 3.2.1.18) (Cytosolic sialidase) (N-acetyl-alpha-neuraminidase 2) | 5 | UniProt NCBI |
| LRRC15 | Leucine-rich repeat-containing protein 15 (Leucine-rich repeat protein induced by beta-amyloid homolog) (hLib) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0003777 | 0.0499631138006 | 0.153846153846 | HEPHL1 DSG4 | Pili torti |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap |
|---|---|---|---|---|
| DUSP14 | CALHM4 | 0.996 | ||
| PLCD1 | DUSP14 | 0.993 | 0.116 |
structurally_consistent (dimer)
|
| NEU2 | CRYBG1 | 0.993 | ||
| S100A3 | DSG4 | 0.992 | ||
| NEU2 | CALHM4 | 0.991 | ||
| NEU2 | LYG2 | 0.991 |
structurally_consistent (Q9UKA2)
|
|
| NEU2 | S100A3 | 0.99 | ||
| SELENBP1 | LYG2 | 0.989 |
structurally_consistent (Q9UKA2)
|
|
| HEPHL1 | DUSP14 | 0.988 |
structurally_consistent (dimer)
|
|
| CALHM4 | CRYBG1 | 0.986 | ||
| CALHM4 | IL31RA | 0.984 | ||
| S100A3 | LRRC15 | 0.983 | ||
| NEU2 | PLCD1 | 0.98 | ||
| HEPHL1 | CRYBG1 | 0.979 | ||
| SELENBP1 | DSG4 | 0.979 | ||
| CSGALNACT1 | CALHM4 | 0.979 | ||
| CSGALNACT1 | LYG2 | 0.978 | ||
| DUSP14 | DSG4 | 0.978 | ||
| S100A3 | CRYBG1 | 0.978 | 0.056 | |
| DHRS12 | HEPHL1 | 0.978 | ||
| LRRC15 | LYG2 | 0.978 |
structurally_consistent (Q9UHN1)
|
|
| LRRC15 | CALHM4 | 0.978 | ||
| CRYBG1 | LYG2 | 0.978 | ||
| PLCD1 | IL31RA | 0.977 | ||
| PLCD1 | DHRS12 | 0.977 | ||
| CSGALNACT1 | CRYBG1 | 0.977 | 0.04 | |
| OR51E2 | S100A3 | 0.976 | ||
| SELENBP1 | S100A3 | 0.976 | 0.034 | |
| DUSP14 | IL31RA | 0.976 |
structurally_consistent (Q6MZM0)
|
|
| S100A3 | IL31RA | 0.975 | ||
| S100A3 | CALHM4 | 0.975 | ||
| DUSP14 | LYG2 | 0.975 | ||
| PLCD1 | LYG2 | 0.975 | ||
| PLCD1 | HEPHL1 | 0.975 | ||
| PLCD1 | S100A3 | 0.975 | 0.046 | |
| SELENBP1 | CALHM4 | 0.975 | ||
| SELENBP1 | PLCD1 | 0.974 | 0.076 |
structurally_consistent (Q9UKA2)
|
| DHRS12 | S100A3 | 0.974 | ||
| NEU2 | HEPHL1 | 0.974 | ||
| DHRS12 | CALHM4 | 0.974 | ||
| NEU2 | CSGALNACT1 | 0.974 | ||
| SELENBP1 | DUSP14 | 0.973 | 0.072 |
structurally_consistent (Q9UKA2)
|
| LRRC15 | IL31RA | 0.973 | ||
| PLCD1 | CALHM4 | 0.973 | ||
| PLCD1 | LRRC15 | 0.972 | ||
| IL31RA | DSG4 | 0.972 | ||
| PLCD1 | CSGALNACT1 | 0.971 | ||
| S100A3 | LYG2 | 0.971 | ||
| NEU2 | DSG4 | 0.97 | ||
| S100A3 | HEPHL1 | 0.969 | ||
| HEPHL1 | CALHM4 | 0.969 | ||
| HEPHL1 | DSG4 | 0.969 | ||
| HEPHL1 | LYG2 | 0.968 | ||
| CALHM4 | DSG4 | 0.968 | ||
| S100A3 | CSGALNACT1 | 0.967 | 0.07 | |
| LYG2 | DSG4 | 0.967 | ||
| PLCD1 | CRYBG1 | 0.966 | 0.06 | |
| HEPHL1 | CSGALNACT1 | 0.966 | ||
| SELENBP1 | LRRC15 | 0.965 | ||
| HEPHL1 | IL31RA | 0.965 |
structurally_consistent (dimer)
|
|
| CALHM4 | LYG2 | 0.964 | ||
| LYG2 | IL31RA | 0.964 | ||
| S100A3 | DUSP14 | 0.96 | 0.1 | |
| NEU2 | LRRC15 | 0.959 | ||
| NEU2 | DUSP14 | 0.959 |
structurally_consistent (Q9UKA2)
|
|
| PLCD1 | DSG4 | 0.958 | ||
| LRRC15 | DUSP14 | 0.958 |
structurally_consistent (dimer)
|
|
| CSGALNACT1 | DSG4 | 0.948 | ||
| DUSP14 | CRYBG1 | 0.946 | 0.0420722891566 | |
| SELENBP1 | HEPHL1 | 0.94 | ||
| LRRC15 | HEPHL1 | 0.937 | ||
| DHRS12 | DSG4 | 0.927 | ||
| LRRC15 | DSG4 | 0.926 | ||
| OR51E2 | DSG4 | 0.921 | ||
| SELENBP1 | CSGALNACT1 | 0.916 | 0.058 | |
| CRYBG1 | DSG4 | 0.913 | ||
| OR51E2 | LRRC15 | 0.902 | ||
| LRRC15 | CRYBG1 | 0.895 | ||
| LRRC15 | CSGALNACT1 | 0.836 | ||
| SELENBP1 | CRYBG1 | 0.817 | 0.07 | |
| SELENBP1 | IL31RA | 0.814 | ||
| DHRS12 | LRRC15 | 0.801 | ||
| DUSP14 | CSGALNACT1 | 0.797 | 0.116 | |
| NEU2 | SELENBP1 | 0.77 | ||
| OR51E2 | CALHM4 | 0.722 | ||
| CRYBG1 | IL31RA | 0.707 | ||
| NEU2 | IL31RA | 0.667 | ||
| OR51E2 | HEPHL1 | 0.571 | ||
| OR51E2 | DUSP14 | 0.443 | ||
| NEU2 | DHRS12 | 0.05 |
Related Complexes