hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06174.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SLC35B3 | Adenosine 3'-phospho 5'-phosphosulfate transporter 2 (3'-phosphoadenosine 5'-phosphosulfate transporter) (PAPS transporter 2) (Solute carrier family 35 member B3) | 5 | UniProt NCBI |
| TRMT10C | tRNA methyltransferase 10 homolog C (HBV pre-S2 trans-regulated protein 2) (Mitochondrial ribonuclease P protein 1) (Mitochondrial RNase P protein 1) (RNA (guanine-9-)-methyltransferase domain-containing protein 1) (Renal carcinoma antigen NY-REN-49) (mRNA methyladenosine-N(1)-methyltransferase) (EC 2.1.1.-) (tRNA (adenine(9)-N(1))-methyltransferase) (EC 2.1.1.218) (tRNA (guanine(9)-N(1))-methyltransferase) (EC 2.1.1.221) | 5 | UniProt NCBI |
| HSD17B10 | 3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35) (17-beta-estradiol 17-dehydrogenase) (EC 1.1.1.62) (2-methyl-3-hydroxybutyryl-CoA dehydrogenase) (MHBD) (3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))) (EC 1.1.1.239) (3-hydroxy-2-methylbutyryl-CoA dehydrogenase) (EC 1.1.1.178) (3-hydroxyacyl-CoA dehydrogenase type II) (3alpha(or 20beta)-hydroxysteroid dehydrogenase) (EC 1.1.1.53) (7-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.159) (Endoplasmic reticulum-associated amyloid beta-peptide-binding protein) (Mitochondrial ribonuclease P protein 2) (Mitochondrial RNase P protein 2) (Short chain dehydrogenase/reductase family 5C member 1) (Short-chain type dehydrogenase/reductase XH98G2) (Type II HADH) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7429 | 3.41752350426e-06 | 0.666666666667 | TRMT10C HSD17B10 | HSD17B10-TRMT10C complex |
| CORUM:7428 | 1.02521027753e-05 | 0.666666666667 | TRMT10C HSD17B10 | mtRNase P |
| REAC:R-HSA-6785470 | 6.81752388431e-05 | 0.666666666667 | TRMT10C HSD17B10 | tRNA processing in the mitochondrion |
| REAC:R-HSA-6787450 | 0.000190864539041 | 0.666666666667 | TRMT10C HSD17B10 | tRNA modification in the mitochondrion |
| REAC:R-HSA-8868766 | 0.000306718584473 | 0.666666666667 | TRMT10C HSD17B10 | rRNA processing in the mitochondrion |
| GO:0030678 | 0.00421361424067 | 0.666666666667 | TRMT10C HSD17B10 | mitochondrial ribonuclease P complex |
| GO:0097745 | 0.00421361424067 | 0.666666666667 | TRMT10C HSD17B10 | mitochondrial tRNA 5'-end processing |
| GO:0000964 | 0.00842684400117 | 0.666666666667 | TRMT10C HSD17B10 | mitochondrial RNA 5'-end processing |
| GO:0070901 | 0.00842684400117 | 0.666666666667 | TRMT10C HSD17B10 | mitochondrial tRNA methylation |
| GO:1990180 | 0.00842684400117 | 0.666666666667 | TRMT10C HSD17B10 | mitochondrial tRNA 3'-end processing |
| GO:0000965 | 0.0210651876021 | 0.666666666667 | TRMT10C HSD17B10 | mitochondrial RNA 3'-end processing |
| GO:0042780 | 0.0210651876021 | 0.666666666667 | TRMT10C HSD17B10 | tRNA 3'-end processing |
| GO:0043527 | 0.0294899169624 | 0.666666666667 | TRMT10C HSD17B10 | tRNA methyltransferase complex |
| REAC:R-HSA-72306 | 0.0329299631783 | 0.666666666667 | TRMT10C HSD17B10 | tRNA processing |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TRMT10C | HSD17B10 | 0.998 | 0.182 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM |
| SLC35B3 | TRMT10C | 0.958 | 0.14 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| SLC35B3 | HSD17B10 | 0.001 | 0.098 | bioplex3_HEK293 bioplex () bioplex3_HCT116 gupta_WMM |
Related Complexes