hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06180.1
Complex Portal: CPX-23711
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GOPC | Golgi-associated PDZ and coiled-coil motif-containing protein (CFTR-associated ligand) (Fused in glioblastoma) (PDZ protein interacting specifically with TC10) (PIST) | 5 | UniProt NCBI |
| CD247 | T-cell surface glycoprotein CD3 zeta chain (T-cell receptor T3 zeta chain) (CD antigen CD247) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5627083 | 0.0499419797295 | 0.5 | GOPC | RHO GTPases regulate CFTR trafficking |
| CORUM:2489 | 0.0499419797295 | 0.5 | CD247 | NCR3-CD247 complex |
| CORUM:7417 | 0.0499419797295 | 0.5 | GOPC | CFTR-GOPC-STX6 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CD247 | GOPC | 0.954 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| GOPC | huMAP3_05405.1 huMAP3_06180.1 huMAP3_06658.1 huMAP3_07452.1 huMAP3_07942.1 huMAP3_11017.1 |
| CD247 | huMAP3_00000.1 huMAP3_05243.1 huMAP3_06180.1 |