hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_06186.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| WTIP | Wilms tumor protein 1-interacting protein (WT1-interacting protein) | 5 | UniProt NCBI |
| SFRP4 | Secreted frizzled-related protein 4 (sFRP-4) (Frizzled protein, human endometrium) (FrpHE) | 5 | UniProt NCBI |
| ZNF580 | Zinc finger protein 580 (LDL-induced EC protein) | 5 | UniProt NCBI |
| LIMD1 | LIM domain-containing protein 1 | 5 | UniProt NCBI |
| PPP2R3A | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha (PP2A subunit B isoform PR72/PR130) (PP2A subunit B isoform R3 isoform) (PP2A subunit B isoforms B''-PR72/PR130) (PP2A subunit B isoforms B72/B130) (Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04392 | 0.00147248543337 | 0.4 | LIMD1 WTIP | Hippo signaling pathway - multiple species |
| REAC:R-HSA-1234176 | 0.0294410858888 | 0.4 | LIMD1 WTIP | Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha |
| REAC:R-HSA-1234174 | 0.0363707033179 | 0.4 | LIMD1 WTIP | Cellular response to hypoxia |
| KEGG:04390 | 0.0471742362289 | 0.4 | LIMD1 WTIP | Hippo signaling pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PPP2R3A | LIMD1 | 0.999 | 0.108 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 |
| PPP2R3A | SFRP4 | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PPP2R3A | ZNF580 | 0.994 | 0.094 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| PPP2R3A | WTIP | 0.986 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ZNF580 | WTIP | 0.572 | bioplex_WMM bioplex3_WMM WMM_only | |
| WTIP | LIMD1 | 0.188 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| ZNF580 | LIMD1 | 0.143 | 0.05 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes