hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_06190.1

Complex Portal: CPX-25453

Confidence: Very High

Genename	Protein Name	Uniprot Annotation Score	Links
APOC3	Apolipoprotein C-III (Apo-CIII) (ApoC-III) (Apolipoprotein C3)	5	UniProt NCBI
MATN2	Matrilin-2	5	UniProt NCBI
THBS4	Thrombospondin-4	5	UniProt NCBI
ADSS1	Adenylosuccinate synthetase isozyme 1 (AMPSase 1) (AdSS 1) (EC 6.3.4.4) (Adenylosuccinate synthetase, basic isozyme) (Adenylosuccinate synthetase, muscle isozyme) (M-type adenylosuccinate synthetase) (Adenylosuccinate synthetase-like 1) (AdSSL1) (IMP--aspartate ligase 1)	5	UniProt NCBI
PLG	Plasminogen (EC 3.4.21.7) [Cleaved into: Plasmin heavy chain A; Activation peptide; Angiostatin; Plasmin heavy chain A, short form; Plasmin light chain B]	5	UniProt NCBI
ITIH1	Inter-alpha-trypsin inhibitor heavy chain H1 (ITI heavy chain H1) (ITI-HC1) (Inter-alpha-inhibitor heavy chain 1) (Inter-alpha-trypsin inhibitor complex component III) (Serum-derived hyaluronan-associated protein) (SHAP)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-186797	0.0170393864121	0.4	THBS4 PLG	Signaling by PDGF
GO:0062023	0.043388817269	0.8	MATN2 PLG APOC3 THBS4	collagen-containing extracellular matrix

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap	Evidence
MATN2	ADSS1	0.997	0.088		bioplex3_WMM bioplex3_HCT116 WMM_only
THBS4	MATN2	0.988			bioplex3_HEK293 bioplex3_WMM WMM_only
ITIH1	MATN2	0.982	0.08		bioplex3_WMM bioplex3_HCT116 WMM_only
MATN2	PLG	0.977	0.168		bioplex3_WMM bioplex3_HCT116 WMM_only
APOC3	MATN2	0.974	0.216		bioplex3_WMM bioplex3_HCT116 WMM_only
ITIH1	PLG	0.851	0.56		bioplex3_WMM WMM_only boldt_WMM
APOC3	ITIH1	0.649	0.338		bioplex3_WMM WMM_only
APOC3	PLG	0.598	0.436		bioplex3_WMM WMM_only
APOC3	ADSS1	0.452	0.09		bioplex3_WMM WMM_only
ITIH1	ADSS1	0.269	0.038		bioplex3_WMM WMM_only
THBS4	ADSS1	0.214			bioplex3_WMM WMM_only
ADSS1	PLG	0.188	0.07		bioplex3_WMM WMM_only
APOC3	THBS4	0.092			bioplex3_WMM WMM_only
ITIH1	THBS4	0.055			bioplex3_WMM WMM_only
THBS4	PLG	0.042			bioplex3_WMM WMM_only

Related Complexes

Genename	Complexes
APOC3	huMAP3_00178.1 huMAP3_00961.1 huMAP3_04159.1 huMAP3_06018.1 huMAP3_06190.1 huMAP3_06724.1 huMAP3_07064.1 huMAP3_07541.1 huMAP3_07603.1 huMAP3_07701.1 huMAP3_08395.1 huMAP3_08796.1 huMAP3_09273.1 huMAP3_09391.1 huMAP3_09531.1 huMAP3_09832.1 huMAP3_10004.1 huMAP3_10101.1 huMAP3_10426.1 huMAP3_10678.1 huMAP3_15040.1
MATN2	huMAP3_00961.1 huMAP3_06018.1 huMAP3_06190.1 huMAP3_06724.1 huMAP3_07064.1 huMAP3_07541.1 huMAP3_07603.1 huMAP3_07647.1 huMAP3_07701.1 huMAP3_08395.1 huMAP3_09273.1 huMAP3_09391.1 huMAP3_09531.1 huMAP3_09832.1 huMAP3_10101.1 huMAP3_10426.1 huMAP3_10678.1 huMAP3_11307.1 huMAP3_15040.1
THBS4	huMAP3_00961.1 huMAP3_02211.1 huMAP3_06018.1 huMAP3_06190.1 huMAP3_06724.1 huMAP3_07064.1 huMAP3_07505.1 huMAP3_07603.1 huMAP3_07647.1 huMAP3_08051.1 huMAP3_09391.1 huMAP3_09832.1 huMAP3_10426.1 huMAP3_11307.1 huMAP3_12316.1 huMAP3_15040.1
ADSS1	huMAP3_03131.1 huMAP3_05178.1 huMAP3_06018.1 huMAP3_06190.1 huMAP3_06724.1 huMAP3_07064.1 huMAP3_07603.1 huMAP3_07647.1 huMAP3_09391.1 huMAP3_09832.1 huMAP3_11307.1 huMAP3_12694.1 huMAP3_15040.1
PLG	huMAP3_06190.1 huMAP3_07701.1 huMAP3_08395.1 huMAP3_08796.1 huMAP3_09273.1 huMAP3_09531.1 huMAP3_09832.1 huMAP3_10101.1 huMAP3_10678.1 huMAP3_13521.1 huMAP3_15040.1
ITIH1	huMAP3_00178.1 huMAP3_00961.1 huMAP3_02811.1 huMAP3_06018.1 huMAP3_06190.1 huMAP3_06724.1 huMAP3_07064.1 huMAP3_07541.1 huMAP3_07603.1 huMAP3_07701.1 huMAP3_08395.1 huMAP3_08796.1 huMAP3_09273.1 huMAP3_09391.1 huMAP3_09531.1 huMAP3_09832.1 huMAP3_10101.1 huMAP3_10426.1 huMAP3_10678.1 huMAP3_15040.1