hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06191.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SPATA46 | Spermatogenesis-associated protein 46 | 4 | UniProt NCBI |
| CSNK1A1L | Casein kinase I isoform alpha-like (CKI-alpha-like) (EC 2.7.11.1) (CK1) | 5 | UniProt NCBI |
| MDM4 | Protein Mdm4 (Double minute 4 protein) (Mdm2-like p53-binding protein) (Protein Mdmx) (p53-binding protein Mdm4) | 5 | UniProt NCBI |
| CSNK1A1 | Casein kinase I isoform alpha (CKI-alpha) (EC 2.7.11.1) (CK1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4844 | 0.00110807642161 | 0.5 | CSNK1A1L CSNK1A1 | Influence of laminopathies on Wnt signaling |
| WP:WP4249 | 0.00169541860832 | 0.5 | CSNK1A1L CSNK1A1 | Hedgehog signaling pathway |
| KEGG:04340 | 0.00247340401034 | 0.5 | CSNK1A1L CSNK1A1 | Hedgehog signaling pathway |
| WP:WP4879 | 0.0027493593259 | 0.5 | CSNK1A1L CSNK1A1 | Overlap between signal transduction pathways contributing to LMNA laminopathies |
| WP:WP5087 | 0.0029183957539 | 0.75 | CSNK1A1L CSNK1A1 MDM4 | Pleural mesothelioma |
| WP:WP4216 | 0.00561306746582 | 0.5 | CSNK1A1L CSNK1A1 | Chromosomal and microsatellite instability in colorectal cancer |
| WP:WP4336 | 0.00685264055756 | 0.5 | CSNK1A1L CSNK1A1 | ncRNAs involved in Wnt signaling in hepatocellular carcinoma |
| WP:WP4258 | 0.00862655865142 | 0.5 | CSNK1A1L CSNK1A1 | lncRNA in canonical Wnt signaling and colorectal cancer |
| KEGG:05224 | 0.0198400959038 | 0.5 | CSNK1A1L CSNK1A1 | Breast cancer |
| KEGG:05226 | 0.0211069184789 | 0.5 | CSNK1A1L CSNK1A1 | Gastric cancer |
| WP:WP4262 | 0.0221503925292 | 0.5 | CSNK1A1L CSNK1A1 | Breast cancer pathway |
| KEGG:04310 | 0.0276522587106 | 0.5 | CSNK1A1L CSNK1A1 | Wnt signaling pathway |
| KEGG:05225 | 0.0310562109 | 0.5 | CSNK1A1L CSNK1A1 | Hepatocellular carcinoma |
| CORUM:7250 | 0.049938562206 | 0.25 | MDM4 | ESR1-MDM4 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MDM4 | SPATA46 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| CSNK1A1 | SPATA46 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| MDM4 | CSNK1A1 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CSNK1A1L | CSNK1A1 | 0.983 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| MDM4 | CSNK1A1L | 0.973 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes