hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_06207.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ALDH6A1 | Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial (MMSDH) (EC 1.2.1.27) (Aldehyde dehydrogenase family 6 member A1) (Malonate-semialdehyde dehydrogenase [acylating]) | 5 | UniProt NCBI |
| ALDH2 | Aldehyde dehydrogenase, mitochondrial (EC 1.2.1.3) (ALDH class 2) (ALDH-E2) (ALDHI) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00410 | 5.70619627602e-05 | 1.0 | ALDH6A1 ALDH2 | beta-Alanine metabolism |
| KEGG:00280 | 0.00016825963378 | 1.0 | ALDH6A1 ALDH2 | Valine, leucine and isoleucine degradation |
| KEGG:00340 | 0.0356198329076 | 0.5 | ALDH2 | Histidine metabolism |
| WP:WP4966 | 0.0373151717536 | 0.5 | ALDH2 | Fluoroacetic acid toxicity |
| KEGG:00770 | 0.0403663802771 | 0.5 | ALDH2 | Pantothenate and CoA biosynthesis |
| REAC:R-HSA-380612 | 0.0499419797295 | 0.5 | ALDH2 | Metabolism of serotonin |
| REAC:R-HSA-380615 | 0.0499419797295 | 0.5 | ALDH2 | Serotonin clearance from the synaptic cleft |
| HP:0001033 | 0.0499436884913 | 0.5 | ALDH2 | Facial flushing after alcohol intake |
| HP:0003533 | 0.0499436884913 | 0.5 | ALDH2 | Reduced acetaldehyde dehydrogenase level |
| HP:0020079 | 0.0499436884913 | 0.5 | ALDH6A1 | Beta-alaninuria |
| HP:0045034 | 0.0499436884913 | 0.5 | ALDH6A1 | Elevated urinary aminoisobutyric acid |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ALDH6A1 | ALDH2 | 0.985 | 0.232 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM fraction |
Related Complexes
| Genename | Complexes |
|---|---|
| ALDH6A1 | huMAP3_02557.1 huMAP3_06207.1 huMAP3_13307.1 |
| ALDH2 | huMAP3_03117.1 huMAP3_04242.1 huMAP3_05942.1 huMAP3_06207.1 huMAP3_10569.1 huMAP3_12502.1 huMAP3_13307.1 huMAP3_15040.1 |