hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06220.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MIA3 | Transport and Golgi organization protein 1 homolog (TANGO1) (C219-reactive peptide) (D320) (Melanoma inhibitory activity protein 3) | 5 | UniProt NCBI |
| CTAGE6 | cTAGE family member 6 (Protein cTAGE-6) | 3 | UniProt NCBI |
| CTAGE1 | cTAGE family member 2 (Protein cTAGE-2) (Cancer/testis antigen 21.2) (CT21.2) | 3 | UniProt NCBI |
| MIA2 | Melanoma inhibitory activity protein 2 (MIA protein 2) (CTAGE family member 5 ER export factor) (Cutaneous T-cell lymphoma-associated antigen 5) (Meningioma-expressed antigen 6/11) | 5 | UniProt NCBI |
| CTAGE8 | cTAGE family member 8 (Protein cTAGE-8) | 2 | UniProt NCBI |
| ANO6 | Anoctamin-6 (Small-conductance calcium-activated nonselective cation channel) (SCAN channel) (Transmembrane protein 16F) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0070971 | 3.54959615011e-09 | 0.833333333333 | CTAGE8 MIA3 MIA2 CTAGE6 CTAGE1 | endoplasmic reticulum exit site |
| GO:0035459 | 9.1660568716e-09 | 0.833333333333 | CTAGE8 MIA3 MIA2 CTAGE6 CTAGE1 | vesicle cargo loading |
| GO:0006888 | 9.39170949702e-06 | 0.833333333333 | CTAGE8 MIA3 MIA2 CTAGE6 CTAGE1 | endoplasmic reticulum to Golgi vesicle-mediated transport |
| GO:0140352 | 8.77454088933e-05 | 1.0 | CTAGE8 CTAGE6 MIA3 CTAGE1 MIA2 ANO6 | export from cell |
| GO:0009306 | 0.000128777727546 | 0.833333333333 | CTAGE8 MIA3 MIA2 CTAGE6 CTAGE1 | protein secretion |
| GO:0035592 | 0.000132089122668 | 0.833333333333 | CTAGE8 MIA3 MIA2 CTAGE6 CTAGE1 | establishment of protein localization to extracellular region |
| GO:0071692 | 0.000149682230544 | 0.833333333333 | CTAGE8 MIA3 MIA2 CTAGE6 CTAGE1 | protein localization to extracellular region |
| GO:0048193 | 0.00061299016503 | 0.833333333333 | CTAGE8 MIA3 MIA2 CTAGE6 CTAGE1 | Golgi vesicle transport |
| GO:0016192 | 0.00887756788753 | 1.0 | CTAGE8 CTAGE6 MIA3 CTAGE1 MIA2 ANO6 | vesicle-mediated transport |
| REAC:R-HSA-5694530 | 0.00902151290218 | 0.333333333333 | MIA3 MIA2 | Cargo concentration in the ER |
| GO:0032940 | 0.00912898656047 | 0.833333333333 | CTAGE8 MIA3 MIA2 CTAGE6 CTAGE1 | secretion by cell |
| GO:0046903 | 0.0145052804479 | 0.833333333333 | CTAGE8 MIA3 MIA2 CTAGE6 CTAGE1 | secretion |
| GO:0071702 | 0.0264962382684 | 1.0 | CTAGE8 CTAGE6 MIA3 CTAGE1 MIA2 ANO6 | organic substance transport |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CTAGE6 | MIA2 | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MIA3 | MIA2 | 0.996 | 0.316 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| MIA2 | ANO6 | 0.993 | 0.058 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM |
| CTAGE6 | MIA3 | 0.991 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| MIA3 | ANO6 | 0.977 | 0.0641797752809 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM |
| MIA2 | CTAGE8 | 0.974 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CTAGE1 | MIA2 | 0.955 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CTAGE1 | CTAGE8 | 0.557 | bioplex_WMM bioplex3_WMM WMM_only | |
| MIA3 | CTAGE8 | 0.143 | bioplex_WMM bioplex3_WMM WMM_only | |
| MIA3 | CTAGE1 | 0.143 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes