hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_06234.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CTR9 | RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) | 5 | UniProt NCBI |
| CDC73 | Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein) | 5 | UniProt NCBI |
| ELOA | Elongin-A (EloA) (Elongin 110 kDa subunit) (RNA polymerase II transcription factor SIII subunit A1) (SIII p110) (Transcription elongation factor B polypeptide 3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-112382 | 1.365277865e-05 | 1.0 | CTR9 ELOA CDC73 | Formation of RNA Pol II elongation complex |
| REAC:R-HSA-75955 | 1.365277865e-05 | 1.0 | CTR9 ELOA CDC73 | RNA Polymerase II Transcription Elongation |
| CORUM:1167 | 3.41705576683e-05 | 0.666666666667 | CTR9 CDC73 | Paf complex |
| REAC:R-HSA-674695 | 3.68984307198e-05 | 1.0 | CTR9 ELOA CDC73 | RNA Polymerase II Pre-transcription Events |
| GO:0008023 | 0.00155858646605 | 1.0 | CTR9 ELOA CDC73 | transcription elongation factor complex |
| WP:WP2853 | 0.00738685655077 | 0.666666666667 | CTR9 CDC73 | Endoderm differentiation |
| REAC:R-HSA-8866654 | 0.00973406489476 | 0.666666666667 | CTR9 CDC73 | E3 ubiquitin ligases ubiquitinate target proteins |
| REAC:R-HSA-8852135 | 0.0183561585619 | 0.666666666667 | CTR9 CDC73 | Protein ubiquitination |
| GO:0016593 | 0.0294899169624 | 0.666666666667 | CTR9 CDC73 | Cdc73/Paf1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CTR9 | CDC73 | 1.0 | 0.786 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM boldt youn_WMM hein () Malo bioplex3_HCT116 fraction boldt_WMM |
| CTR9 | ELOA | 0.985 | 0.342 | hein_WMM bioplex3_WMM boldt youn_WMM hein () boldt_WMM |
| CDC73 | ELOA | 0.951 | 0.336 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only |
Related Complexes