hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06263.1
Complex Portal: CPX-23128
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| HIGD1A | HIG1 domain family member 1A, mitochondrial (Hypoxia-inducible gene 1 protein) (RCF1 homolog A) (RCF1a) | 5 | UniProt NCBI |
| AASS | Alpha-aminoadipic semialdehyde synthase, mitochondrial (LKR/SDH) [Includes: Lysine ketoglutarate reductase (LKR) (LOR) (EC 1.5.1.8); Saccharopine dehydrogenase (SDH) (EC 1.5.1.9)] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0012403 | 0.0499436884913 | 0.5 | AASS | Decreased urine alpha-ketoglutarate concentration |
| HP:0031867 | 0.0499436884913 | 0.5 | AASS | Neck hypertonia |
| HP:0032397 | 0.0499436884913 | 0.5 | AASS | Citrullinuria |
| HP:0500151 | 0.0499436884913 | 0.5 | AASS | Hypercystinemia |
| HP:0500202 | 0.0499436884913 | 0.5 | AASS | Abnormal CSF arginine concentration |
| HP:0500204 | 0.0499436884913 | 0.5 | AASS | Decreased CSF arginine concentration |
| HP:0500243 | 0.0499436884913 | 0.5 | AASS | Abnormal CSF ornithine concentration |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| AASS | HIGD1A | 0.958 | 0.048 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM |
Related Complexes