hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06265.1
Complex Portal: CPX-15230
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ASAP1 | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP) | 5 | UniProt NCBI |
| PRR12 | Proline-rich protein 12 | 4 | UniProt NCBI |
| SHANK3 | SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) | 5 | UniProt NCBI |
| ARHGAP12 | Rho GTPase-activating protein 12 (Rho-type GTPase-activating protein 12) | 5 | UniProt NCBI |
| NKX2-5 | Homeobox protein Nkx-2.5 (Cardiac-specific homeobox) (Homeobox protein CSX) (Homeobox protein NK-2 homolog E) | 5 | UniProt NCBI |
| ARHGAP27 | Rho GTPase-activating protein 27 (CIN85-associated multi-domain-containing Rho GTPase-activating protein 1) (Rho-type GTPase-activating protein 27) (SH3 domain-containing protein 20) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0100786 | 0.0035231963033 | 0.4 | PRR12 NKX2-5 | Hypersomnia |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ARHGAP12 | ARHGAP27 | 0.987 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| ARHGAP12 | ASAP1 | 0.983 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| NKX2-5 | ARHGAP12 | 0.972 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| PRR12 | ARHGAP12 | 0.964 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| PRR12 | ARHGAP27 | 0.415 | 0.176 | bioplex3_WMM WMM_only | |
| NKX2-5 | ASAP1 | 0.262 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ARHGAP27 | ASAP1 | 0.25 | 0.144 | bioplex3_WMM WMM_only | |
| PRR12 | ASAP1 | 0.113 | 0.124 | bioplex3_WMM WMM_only | |
| NKX2-5 | ARHGAP27 | 0.113 | bioplex3_WMM WMM_only | ||
| NKX2-5 | PRR12 | 0.095 | bioplex3_WMM WMM_only |
Related Complexes