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hu.MAP 3.0
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hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):
Enrichment (ex. cilium):
Protein (ex. Centrosomal protein):
Complex:
huMAP3_06273.1
Confidence:
Very High
?
Proteins
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Genename
Protein Name
Uniprot Annotation Score
Links
GAB2
GRB2-associated-binding protein 2 (GRB2-associated binder 2) (Growth factor receptor bound protein 2-associated protein 2) (pp100)
5
UniProt
NCBI
GRAP2
GRB2-related adapter protein 2 (Adapter protein GRID) (GRB-2-like protein) (GRB2L) (GRBLG) (GRBX) (Grf40 adapter protein) (Grf-40) (Growth factor receptor-binding protein) (Hematopoietic cell-associated adapter protein GrpL) (P38) (Protein GADS) (SH3-SH2-SH3 adapter Mona)
5
UniProt
NCBI
USP8
Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (hUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8)
5
UniProt
NCBI
Showing 1 to 3 of 3 entries
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Enrichments
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Term ID
Corrected Pval
Fraction Complex Coverage
Proteins
Term Name
WP:WP69
0.00206734131669
0.666666666667
GAB2 GRAP2
T cell receptor signaling pathway
REAC:R-HSA-9680350
0.00257431960226
0.666666666667
GAB2 GRAP2
Signaling by CSF1 (M-CSF) in myeloid cells
REAC:R-HSA-9607240
0.0033773260227
0.666666666667
GAB2 GRAP2
FLT3 Signaling
REAC:R-HSA-1433557
0.00428896488724
0.666666666667
GAB2 GRAP2
Signaling by SCF-KIT
REAC:R-HSA-9006934
0.00622622698696
1.0
GAB2 GRAP2 USP8
Signaling by Receptor Tyrosine Kinases
WP:WP437
0.0115871748317
0.666666666667
GAB2 USP8
EGF EGFR signaling pathway
REAC:R-HSA-2454202
0.041419681818
0.666666666667
GAB2 GRAP2
Fc epsilon receptor (FCERI) signaling
Showing 1 to 7 of 7 entries
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Edges
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Protein 1
Protein 2
Score
?
ProteomeHD
?
Evidence
?
GAB2
GRAP2
0.999
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
GRAP2
USP8
0.999
0.176
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116
GAB2
USP8
0.98
0.178
bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only
Showing 1 to 3 of 3 entries
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Related Complexes
Genename
Complexes
GAB2
huMAP3_02697.1
huMAP3_05278.1
huMAP3_05489.1
huMAP3_06273.1
huMAP3_10890.1
huMAP3_12452.1
huMAP3_12897.1
GRAP2
huMAP3_05278.1
huMAP3_05489.1
huMAP3_06273.1
huMAP3_10890.1
huMAP3_12452.1
USP8
huMAP3_06273.1
huMAP3_10890.1
huMAP3_11326.1
huMAP3_12452.1
huMAP3_13310.1