hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_06314.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FAXC | Failed axon connections homolog | 3 | UniProt NCBI |
| SLC2A8 | Solute carrier family 2, facilitated glucose transporter member 8 (Glucose transporter type 8) (GLUT-8) (Glucose transporter type X1) | 5 | UniProt NCBI |
| TRAK1 | Trafficking kinesin-binding protein 1 (106 kDa O-GlcNAc transferase-interacting protein) (Protein Milton) | 5 | UniProt NCBI |
| SAMM50 | Sorting and assembly machinery component 50 homolog (Transformation-related gene 3 protein) (TRG-3) | 5 | UniProt NCBI |
| IMMT | MICOS complex subunit MIC60 (Cell proliferation-inducing gene 4/52 protein) (Mitochondrial inner membrane protein) (Mitofilin) (p87/89) | 5 | UniProt NCBI |
| MTX2 | Metaxin-2 (Mitochondrial outer membrane import complex protein 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6249 | 5.6068011168e-07 | 0.5 | MTX2 SAMM50 IMMT | MIB complex |
| REAC:R-HSA-8949613 | 2.85755298292e-05 | 0.5 | MTX2 SAMM50 IMMT | Cristae formation |
| GO:0001401 | 0.00042234232358 | 0.5 | MTX2 SAMM50 IMMT | SAM complex |
| GO:0140275 | 0.00042234232358 | 0.5 | MTX2 SAMM50 IMMT | MIB complex |
| REAC:R-HSA-1592230 | 0.000714100505716 | 0.5 | MTX2 SAMM50 IMMT | Mitochondrial biogenesis |
| GO:0005742 | 0.00218580514948 | 0.5 | MTX2 SAMM50 IMMT | mitochondrial outer membrane translocase complex |
| GO:0098799 | 0.00254971303757 | 0.5 | MTX2 SAMM50 IMMT | outer mitochondrial membrane protein complex |
| GO:0007007 | 0.0188853212627 | 0.5 | MTX2 SAMM50 IMMT | inner mitochondrial membrane organization |
| REAC:R-HSA-1852241 | 0.0232310173112 | 0.5 | MTX2 SAMM50 IMMT | Organelle biogenesis and maintenance |
| KEGG:04137 | 0.0339543001219 | 0.333333333333 | MTX2 SAMM50 | Mitophagy - animal |
| HPA:0241103 | 0.0353034489875 | 0.666666666667 | IMMT TRAK1 MTX2 SAMM50 | heart muscle; cardiomyocytes[High] |
| REAC:R-HSA-1268020 | 0.0452196184553 | 0.333333333333 | MTX2 SAMM50 | Mitochondrial protein import |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SAMM50 | MTX2 | 1.0 | 0.958 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 boldt_WMM |
| IMMT | MTX2 | 1.0 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM boldt hein () bioplex3_HCT116 fraction boldt_WMM | |
| SAMM50 | IMMT | 0.998 | hein_WMM bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| TRAK1 | SAMM50 | 0.997 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TRAK1 | IMMT | 0.993 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TRAK1 | MTX2 | 0.982 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| FAXC | SAMM50 | 0.975 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MTX2 | SLC2A8 | 0.97 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SAMM50 | SLC2A8 | 0.97 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| FAXC | IMMT | 0.968 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| FAXC | MTX2 | 0.96 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| IMMT | SLC2A8 | 0.948 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM WMM_only |
Related Complexes