hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_06321.1
Complex Portal: CPX-20479
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MSTN | Growth/differentiation factor 8 (GDF-8) (Myostatin) | 5 | UniProt NCBI |
| GDF11 | Growth/differentiation factor 11 (GDF-11) (Bone morphogenetic protein 11) (BMP-11) | 5 | UniProt NCBI |
| PDIA6 | Protein disulfide-isomerase A6 (EC 5.3.4.1) (Endoplasmic reticulum protein 5) (ER protein 5) (ERp5) (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7) | 5 | UniProt NCBI |
| PRTG | Protogenin (Protein Shen-Dan) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04060 | 0.0475663770677 | 0.5 | MSTN GDF11 | Cytokine-cytokine receptor interaction |
| CORUM:6078 | 0.049938562206 | 0.25 | PDIA6 | HSPA2-ACR-PDIA6 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MSTN | GDF11 | 0.999 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| MSTN | PRTG | 0.981 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| MSTN | PDIA6 | 0.967 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| GDF11 | PDIA6 | 0.957 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | ||
| GDF11 | PRTG | 0.954 | bioplex3_HEK293 bioplex3_WMM WMM_only | ||
| PRTG | PDIA6 | 0.083 | bioplex3_WMM WMM_only |
Related Complexes