hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_06325.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| VRK1 | Serine/threonine-protein kinase VRK1 (EC 2.7.11.1) (Vaccinia-related kinase 1) | 5 | UniProt NCBI |
| FEN1 | Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (DNase IV) (Flap structure-specific endonuclease 1) (Maturation factor 1) (MF1) (hFEN-1) | 5 | UniProt NCBI |
| NARS1 | Asparagine--tRNA ligase, cytoplasmic (EC 6.1.1.22) (Asparaginyl-tRNA synthetase) (AsnRS) (Asparaginyl-tRNA synthetase 1) | 5 | UniProt NCBI |
| TCEA1 | Transcription elongation factor A protein 1 (Transcription elongation factor S-II protein 1) (Transcription elongation factor TFIIS.o) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0570762 | 0.0115490191121 | 1.0 | VRK1 FEN1 TCEA1 NARS1 | testis; pachytene spermatocytes[>=Medium] |
| HPA:0570761 | 0.0273327385677 | 1.0 | VRK1 FEN1 TCEA1 NARS1 | testis; pachytene spermatocytes[>=Low] |
| CORUM:7101 | 0.049938562206 | 0.25 | VRK1 | AURKB-VRK1 complex |
| CORUM:7102 | 0.049938562206 | 0.25 | VRK1 | SOX2-VRK1 complex |
| CORUM:7103 | 0.049938562206 | 0.25 | VRK1 | NBS1-VRK1 complex |
| CORUM:7104 | 0.049938562206 | 0.25 | VRK1 | NBS1-RNF8-VRK1 complex |
| CORUM:7282 | 0.049938562206 | 0.25 | FEN1 | FEN1-WRN complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TCEA1 | VRK1 | 0.992 | 0.108 | bioplex_WMM bioplex3_WMM fraction |
| FEN1 | VRK1 | 0.984 | 0.106 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction |
| VRK1 | NARS1 | 0.977 | 0.068 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| FEN1 | NARS1 | 0.962 | 0.184 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| FEN1 | TCEA1 | 0.918 | 0.172 | bioplex_WMM bioplex3_WMM fraction treiber_WMM |
| TCEA1 | NARS1 | 0.821 | 0.232 | bioplex_WMM bioplex3_WMM fraction |
Related Complexes