hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06336.1
Complex Portal: CPX-24777
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PRDM10 | PR domain zinc finger protein 10 (EC 2.1.1.-) (PR domain-containing protein 10) (Tristanin) | 5 | UniProt NCBI |
| ZNF770 | Zinc finger protein 770 | 3 | UniProt NCBI |
| ZNF845 | Zinc finger protein 845 | 2 | UniProt NCBI |
| ZNF445 | Zinc finger protein 445 (ZFP445) (Zinc finger protein 168) (Zinc finger protein with KRAB and SCAN domains 15) | 5 | UniProt NCBI |
| ZKSCAN8 | Zinc finger protein with KRAB and SCAN domains 8 (LD5-1) (Zinc finger protein 192) | 5 | UniProt NCBI |
| ZNF236 | Zinc finger protein 236 | 4 | UniProt NCBI |
| ZKSCAN3 | Zinc finger protein with KRAB and SCAN domains 3 (Zinc finger and SCAN domain-containing protein 13) (Zinc finger protein 306) (Zinc finger protein 309) (Zinc finger protein 47 homolog) (Zf47) (Zfp-47) | 5 | UniProt NCBI |
| ZNF197 | Zinc finger protein 197 (Zinc finger protein with KRAB and SCAN domains 9) (ZnF20) (pVHL-associated KRAB domain-containing protein) | 4 | UniProt NCBI |
| ZBTB24 | Zinc finger and BTB domain-containing protein 24 (Zinc finger protein 450) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0000978 | 2.31194798534e-05 | 0.888888888889 | ZNF445 ZNF197 ZKSCAN8 ZBTB24 ZNF236 ZNF845 ZKSCAN3 ZNF770 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0000987 | 2.72818089476e-05 | 0.888888888889 | ZNF445 ZNF197 ZKSCAN8 ZBTB24 ZNF236 ZNF845 ZKSCAN3 ZNF770 | cis-regulatory region sequence-specific DNA binding |
| GO:0000977 | 8.47144207758e-05 | 0.888888888889 | ZNF445 ZNF197 ZKSCAN8 ZBTB24 ZNF236 ZNF845 ZKSCAN3 ZNF770 | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| GO:0003700 | 0.000111001704599 | 0.888888888889 | ZNF445 ZNF197 ZKSCAN8 ZBTB24 ZNF236 ZNF845 ZKSCAN3 ZNF770 | DNA-binding transcription factor activity |
| GO:0000976 | 0.000167113428487 | 0.888888888889 | ZNF445 ZNF197 ZKSCAN8 ZBTB24 ZNF236 ZNF845 ZKSCAN3 ZNF770 | transcription cis-regulatory region binding |
| GO:0001067 | 0.0001684779506 | 0.888888888889 | ZNF445 ZNF197 ZKSCAN8 ZBTB24 ZNF236 ZNF845 ZKSCAN3 ZNF770 | transcription regulatory region nucleic acid binding |
| GO:0006357 | 0.000211457594888 | 1.0 | ZNF445 ZNF197 ZKSCAN3 ZKSCAN8 ZBTB24 ZNF236 ZNF845 PRDM10 ZNF770 | regulation of transcription by RNA polymerase II |
| GO:1990837 | 0.000242760712296 | 0.888888888889 | ZNF445 ZNF197 ZKSCAN8 ZBTB24 ZNF236 ZNF845 ZKSCAN3 ZNF770 | sequence-specific double-stranded DNA binding |
| GO:0006366 | 0.000341817047822 | 1.0 | ZNF445 ZNF197 ZKSCAN3 ZKSCAN8 ZBTB24 ZNF236 ZNF845 PRDM10 ZNF770 | transcription by RNA polymerase II |
| GO:0043565 | 0.000428673884053 | 0.888888888889 | ZNF445 ZNF197 ZKSCAN8 ZBTB24 ZNF236 ZNF845 ZKSCAN3 ZNF770 | sequence-specific DNA binding |
| GO:0003690 | 0.000438043903742 | 0.888888888889 | ZNF445 ZNF197 ZKSCAN8 ZBTB24 ZNF236 ZNF845 ZKSCAN3 ZNF770 | double-stranded DNA binding |
| GO:0140110 | 0.00205034568638 | 0.888888888889 | ZNF445 ZNF197 ZKSCAN8 ZBTB24 ZNF236 ZNF845 ZKSCAN3 ZNF770 | transcription regulator activity |
| GO:0006355 | 0.00303795876717 | 1.0 | ZNF445 ZNF197 ZKSCAN3 ZKSCAN8 ZBTB24 ZNF236 ZNF845 PRDM10 ZNF770 | regulation of DNA-templated transcription |
| GO:2001141 | 0.00320804197401 | 1.0 | ZNF445 ZNF197 ZKSCAN3 ZKSCAN8 ZBTB24 ZNF236 ZNF845 PRDM10 ZNF770 | regulation of RNA biosynthetic process |
| GO:0000981 | 0.0043263538375 | 0.777777777778 | ZNF445 ZNF197 ZKSCAN8 ZNF236 ZNF845 ZKSCAN3 ZNF770 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0006351 | 0.00465537895398 | 1.0 | ZNF445 ZNF197 ZKSCAN3 ZKSCAN8 ZBTB24 ZNF236 ZNF845 PRDM10 ZNF770 | DNA-templated transcription |
| GO:0003677 | 0.00497987143669 | 0.888888888889 | ZNF445 ZNF197 ZKSCAN8 ZBTB24 ZNF236 ZNF845 ZKSCAN3 ZNF770 | DNA binding |
| GO:0032774 | 0.00512577137556 | 1.0 | ZNF445 ZNF197 ZKSCAN3 ZKSCAN8 ZBTB24 ZNF236 ZNF845 PRDM10 ZNF770 | RNA biosynthetic process |
| GO:0051252 | 0.00831592797017 | 1.0 | ZNF445 ZNF197 ZKSCAN3 ZKSCAN8 ZBTB24 ZNF236 ZNF845 PRDM10 ZNF770 | regulation of RNA metabolic process |
| GO:0034654 | 0.0158700258372 | 1.0 | ZNF445 ZNF197 ZKSCAN3 ZKSCAN8 ZBTB24 ZNF236 ZNF845 PRDM10 ZNF770 | nucleobase-containing compound biosynthetic process |
| GO:0018130 | 0.0187008801665 | 1.0 | ZNF445 ZNF197 ZKSCAN3 ZKSCAN8 ZBTB24 ZNF236 ZNF845 PRDM10 ZNF770 | heterocycle biosynthetic process |
| GO:0019438 | 0.0188805671311 | 1.0 | ZNF445 ZNF197 ZKSCAN3 ZKSCAN8 ZBTB24 ZNF236 ZNF845 PRDM10 ZNF770 | aromatic compound biosynthetic process |
| GO:0019219 | 0.0189408029 | 1.0 | ZNF445 ZNF197 ZKSCAN3 ZKSCAN8 ZBTB24 ZNF236 ZNF845 PRDM10 ZNF770 | regulation of nucleobase-containing compound metabolic process |
| GO:1901362 | 0.0245018387601 | 1.0 | ZNF445 ZNF197 ZKSCAN3 ZKSCAN8 ZBTB24 ZNF236 ZNF845 PRDM10 ZNF770 | organic cyclic compound biosynthetic process |
| REAC:R-HSA-212436 | 0.0395263988284 | 0.555555555556 | ZKSCAN3 ZNF445 ZNF770 ZNF197 ZKSCAN8 | Generic Transcription Pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ZNF445 | ZNF197 | 0.995 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | ||
| ZKSCAN8 | ZNF197 | 0.994 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | ||
| ZKSCAN8 | ZNF770 | 0.994 | 0.218 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| ZKSCAN8 | ZNF445 | 0.993 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | ||
| ZKSCAN3 | ZNF197 | 0.99 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZKSCAN8 | ZBTB24 | 0.989 | 0.176 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| ZNF770 | ZNF845 | 0.989 | 0.156 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| ZNF445 | ZNF770 | 0.986 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF445 | ZBTB24 | 0.985 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | ||
| ZKSCAN8 | ZNF845 | 0.982 | 0.142 | hein_WMM bioplex3_WMM WMM_only | |
| ZNF770 | ZBTB24 | 0.98 | 0.176 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| PRDM10 | ZNF845 | 0.974 | 0.132 | hein_WMM bioplex3_WMM WMM_only | |
| PRDM10 | ZBTB24 | 0.973 | 0.09 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| ZNF236 | ZNF197 | 0.973 | hein_WMM bioplex3_WMM WMM_only | ||
| ZKSCAN8 | ZKSCAN3 | 0.973 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF445 | PRDM10 | 0.966 | hein_WMM bioplex3_WMM WMM_only | ||
| ZKSCAN8 | PRDM10 | 0.958 | 0.1 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| ZKSCAN8 | ZNF236 | 0.958 | hein_WMM bioplex3_WMM WMM_only | ||
| ZNF845 | ZBTB24 | 0.953 | 0.132 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| PRDM10 | ZNF236 | 0.949 | hein_WMM bioplex3_WMM WMM_only | ||
| ZKSCAN3 | ZNF445 | 0.947 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ZNF236 | ZBTB24 | 0.943 | hein_WMM bioplex3_WMM WMM_only | ||
| ZNF445 | ZNF845 | 0.938 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | ||
| PRDM10 | ZNF770 | 0.935 | 0.098 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| ZNF197 | ZBTB24 | 0.913 | hein_WMM bioplex3_WMM WMM_only | ||
| ZNF236 | ZNF770 | 0.895 | hein_WMM bioplex3_WMM WMM_only | ||
| PRDM10 | ZNF197 | 0.433 | hein_WMM bioplex3_WMM WMM_only | ||
| ZNF236 | ZNF845 | 0.248 | hein_WMM WMM_only | ||
| ZNF845 | ZNF197 | 0.248 | hein_WMM WMM_only | ||
| ZNF770 | ZNF197 | 0.248 | hein_WMM WMM_only | ||
| ZNF445 | ZNF236 | 0.248 | hein_WMM WMM_only | ||
| ZKSCAN3 | ZNF770 | 0.018 | bioplex3_WMM WMM_only |
Related Complexes