hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06396.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ANKS1B | Ankyrin repeat and sterile alpha motif domain-containing protein 1B (Amyloid-beta protein intracellular domain-associated protein 1) (AIDA-1) (E2A-PBX1-associated protein) (EB-1) | 5 | UniProt NCBI |
| ARHGAP10 | Rho GTPase-activating protein 10 (GTPase regulator associated with focal adhesion kinase 2) (GRAF2) (Graf-related protein 2) (Rho-type GTPase-activating protein 10) | 5 | UniProt NCBI |
| OPHN1 | Oligophrenin-1 | 5 | UniProt NCBI |
| ARHGAP26 | Rho GTPase-activating protein 26 (GTPase regulator associated with focal adhesion kinase) (GRAF1) (Oligophrenin-1-like protein) (Rho-type GTPase-activating protein 26) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9013148 | 0.000453862022785 | 0.75 | ARHGAP10 OPHN1 ARHGAP26 | CDC42 GTPase cycle |
| REAC:R-HSA-8980692 | 0.000453862022785 | 0.75 | ARHGAP10 OPHN1 ARHGAP26 | RHOA GTPase cycle |
| REAC:R-HSA-9013149 | 0.000897810107574 | 0.75 | ARHGAP10 OPHN1 ARHGAP26 | RAC1 GTPase cycle |
| REAC:R-HSA-9012999 | 0.0139104893494 | 0.75 | ARHGAP10 OPHN1 ARHGAP26 | RHO GTPase cycle |
| REAC:R-HSA-9013409 | 0.0140623832262 | 0.5 | ARHGAP26 OPHN1 | RHOJ GTPase cycle |
| REAC:R-HSA-9013406 | 0.0140623832262 | 0.5 | ARHGAP26 OPHN1 | RHOQ GTPase cycle |
| WP:WP2858 | 0.0165681999049 | 0.5 | ANKS1B ARHGAP10 | Ectoderm differentiation |
| REAC:R-HSA-9013026 | 0.0186613511621 | 0.5 | ARHGAP26 OPHN1 | RHOB GTPase cycle |
| REAC:R-HSA-9013106 | 0.0212029570934 | 0.5 | ARHGAP26 OPHN1 | RHOC GTPase cycle |
| REAC:R-HSA-9013404 | 0.0346321697685 | 0.5 | ARHGAP26 OPHN1 | RAC2 GTPase cycle |
| REAC:R-HSA-9013423 | 0.0371865475195 | 0.5 | ARHGAP26 OPHN1 | RAC3 GTPase cycle |
| CORUM:5274 | 0.049938562206 | 0.25 | ARHGAP10 | Cell-cell junction complex (ARHGAP10-CTNNA1) |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ARHGAP26 | OPHN1 | 0.999 | 0.172 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| ARHGAP10 | ARHGAP26 | 0.999 | 0.164 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM |
| ANKS1B | ARHGAP26 | 0.965 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ARHGAP10 | OPHN1 | 0.902 | 0.252 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes