hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06402.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ABCE1 | ATP-binding cassette sub-family E member 1 (EC 3.6.5.-) (2'-5'-oligoadenylate-binding protein) (HuHP68) (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I) | 5 | UniProt NCBI |
| NDST1 | Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 (Glucosaminyl N-deacetylase/N-sulfotransferase 1) (NDST-1) (N-heparan sulfate sulfotransferase 1) (N-HSST 1) ([Heparan sulfate]-glucosamine N-sulfotransferase 1) (HSNST 1) [Includes: Heparan sulfate N-deacetylase 1 (EC 3.5.1.-); Heparan sulfate N-sulfotransferase 1 (EC 2.8.2.8)] | 5 | UniProt NCBI |
| NDST2 | Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 (EC 2.8.2.8) (Glucosaminyl N-deacetylase/N-sulfotransferase 2) (NDST-2) (N-heparan sulfate sulfotransferase 2) (N-HSST 2) [Includes: Heparan sulfate N-deacetylase 2 (EC 3.-.-.-); Heparan sulfate N-sulfotransferase 2 (EC 2.8.2.-)] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00534 | 0.0001601688991 | 0.666666666667 | NDST1 NDST2 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin |
| WP:WP5395 | 0.00079501095268 | 0.666666666667 | NDST1 NDST2 | Glycosaminoglycan synthesis in fibroblasts |
| GO:0050119 | 0.00140460216025 | 0.666666666667 | NDST1 NDST2 | N-acetylglucosamine deacetylase activity |
| REAC:R-HSA-2022928 | 0.00257431960226 | 0.666666666667 | NDST1 NDST2 | HS-GAG biosynthesis |
| REAC:R-HSA-1638091 | 0.00833431912959 | 0.666666666667 | NDST1 NDST2 | Heparan sulfate/heparin (HS-GAG) metabolism |
| GO:0015016 | 0.00842684400117 | 0.666666666667 | NDST1 NDST2 | [heparan sulfate]-glucosamine N-sulfotransferase activity |
| WP:WP702 | 0.0101834993772 | 0.666666666667 | NDST1 NDST2 | Metapathway biotransformation Phase I and II |
| GO:0015014 | 0.0393180950424 | 0.666666666667 | NDST1 NDST2 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process |
| REAC:R-HSA-1630316 | 0.0406752460979 | 0.666666666667 | NDST1 NDST2 | Glycosaminoglycan metabolism |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NDST1 | NDST2 | 0.999 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| ABCE1 | NDST1 | 0.965 | 0.164 | hein_WMM bioplex3_WMM WMM_only |
| ABCE1 | NDST2 | 0.013 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes