hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06422.1
Complex Portal: CPX-12838
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KIF18B | Kinesin-like protein KIF18B | 5 | UniProt NCBI |
| KIF15 | Kinesin-like protein KIF15 (Kinesin-like protein 2) (hKLP2) (Kinesin-like protein 7) (Serologically defined breast cancer antigen NY-BR-62) | 5 | UniProt NCBI |
| KIF13B | Kinesin-like protein KIF13B (Kinesin-like protein GAKIN) | 5 | UniProt NCBI |
| KIFBP | KIF-binding protein (KIF1-binding protein) (Kinesin family binding protein) | 5 | UniProt NCBI |
| KIF18A | Kinesin-like protein KIF18A (Marrow stromal KIF18A) (MS-KIF18A) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-983189 | 1.34717770914e-07 | 0.8 | KIF18B KIF18A KIF15 KIF13B | Kinesins |
| REAC:R-HSA-6811434 | 1.24109632959e-06 | 0.8 | KIF18B KIF18A KIF15 KIF13B | COPI-dependent Golgi-to-ER retrograde traffic |
| KEGG:04814 | 3.50082479815e-06 | 0.8 | KIF18B KIF18A KIF15 KIF13B | Motor proteins |
| REAC:R-HSA-8856688 | 4.24686934885e-06 | 0.8 | KIF18B KIF18A KIF15 KIF13B | Golgi-to-ER retrograde transport |
| GO:0005871 | 8.67338862712e-06 | 0.8 | KIF18B KIF18A KIF15 KIF13B | kinesin complex |
| REAC:R-HSA-983231 | 1.03179988059e-05 | 0.8 | KIF18B KIF18A KIF15 KIF13B | Factors involved in megakaryocyte development and platelet production |
| REAC:R-HSA-6811442 | 2.36864607463e-05 | 0.8 | KIF18B KIF18A KIF15 KIF13B | Intra-Golgi and retrograde Golgi-to-ER traffic |
| GO:0003777 | 3.5523826943e-05 | 0.8 | KIF18B KIF18A KIF15 KIF13B | microtubule motor activity |
| GO:0003774 | 0.000319733015871 | 0.8 | KIF18B KIF18A KIF15 KIF13B | cytoskeletal motor activity |
| GO:0016887 | 0.00118663084114 | 0.8 | KIF18B KIF18A KIF15 KIF13B | ATP hydrolysis activity |
| GO:0005875 | 0.00118663084114 | 0.8 | KIF18B KIF18A KIF15 KIF13B | microtubule associated complex |
| REAC:R-HSA-109582 | 0.00129857214677 | 0.8 | KIF18B KIF18A KIF15 KIF13B | Hemostasis |
| REAC:R-HSA-199991 | 0.00183945180572 | 0.8 | KIF18B KIF18A KIF15 KIF13B | Membrane Trafficking |
| REAC:R-HSA-5653656 | 0.00228321498701 | 0.8 | KIF18B KIF18A KIF15 KIF13B | Vesicle-mediated transport |
| GO:0008017 | 0.0100477300178 | 0.8 | KIF18B KIF18A KIF15 KIF13B | microtubule binding |
| GO:0007017 | 0.0119069088956 | 1.0 | KIFBP KIF18B KIF18A KIF15 KIF13B | microtubule-based process |
| GO:0008092 | 0.0133485794118 | 1.0 | KIFBP KIF18B KIF18A KIF15 KIF13B | cytoskeletal protein binding |
| GO:0007018 | 0.0284935982879 | 0.8 | KIF18B KIF18A KIF15 KIF13B | microtubule-based movement |
| GO:0005874 | 0.0289172689799 | 0.8 | KIF18B KIF18A KIF15 KIF13B | microtubule |
| GO:0015631 | 0.0405744022835 | 0.8 | KIF18B KIF18A KIF15 KIF13B | tubulin binding |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| KIF18A | KIFBP | 1.0 | 0.084 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt hein () bioplex3_HCT116 boldt_WMM |
| KIF13B | KIFBP | 0.999 | 0.038 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| KIF15 | KIFBP | 0.995 | 0.054 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 |
| KIF18B | KIFBP | 0.995 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | ||
| KIF18A | KIF18B | 0.993 | hein_WMM bioplex_WMM bioplex3_WMM hein () | ||
| KIF15 | KIF13B | 0.788 | 0.042 | bioplex_WMM bioplex3_WMM WMM_only | |
| KIF18A | KIF15 | 0.764 | 0.224 |
mutually_exclusive (Q96EK5)
|
bioplex_WMM bioplex3_WMM WMM_only |
| KIF18A | KIF13B | 0.59 | 0.156 | bioplex_WMM bioplex3_WMM WMM_only | |
| KIF18B | KIF15 | 0.14 | bioplex_WMM bioplex3_WMM WMM_only | ||
| KIF18B | KIF13B | 0.086 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
Related Complexes