hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06477.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NUDT21 | Cleavage and polyadenylation specificity factor subunit 5 (Cleavage and polyadenylation specificity factor 25 kDa subunit) (CPSF 25 kDa subunit) (Cleavage factor Im complex 25 kDa subunit) (CFIm25) (Nucleoside diphosphate-linked moiety X motif 21) (Nudix motif 21) (Nudix hydrolase 21) (Pre-mRNA cleavage factor Im 68 kDa subunit) | 5 | UniProt NCBI |
| KHSRP | Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75) | 5 | UniProt NCBI |
| CPSF6 | Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1769 | 1.02521027753e-05 | 0.666666666667 | NUDT21 CPSF6 | CPSF6-ITCH-NUDT21-POLR2A complex |
| CORUM:1767 | 2.05032700758e-05 | 0.666666666667 | NUDT21 CPSF6 | CPSF6-ITCH-NUDT21-POLR2A-UBAP2L complex |
| CORUM:1768 | 3.41705576683e-05 | 0.666666666667 | NUDT21 CPSF6 | CPSF6-EWSR1-ITCH-NUDT21-POLR2A-UBAP2L complex |
| CORUM:1141 | 0.000266433060428 | 0.666666666667 | NUDT21 CPSF6 | CF IIAm complex (Cleavage factor IIAm complex) |
| KEGG:03015 | 0.00311331063035 | 0.666666666667 | NUDT21 CPSF6 | mRNA surveillance pathway |
| GO:1990120 | 0.00421361424067 | 0.666666666667 | NUDT21 CPSF6 | messenger ribonucleoprotein complex assembly |
| GO:0110104 | 0.00842684400117 | 0.666666666667 | NUDT21 CPSF6 | mRNA alternative polyadenylation |
| CORUM:351 | 0.0316415640819 | 0.666666666667 | NUDT21 CPSF6 | Spliceosome |
| HPA:0500703 | 0.047407125424 | 0.666666666667 | CPSF6 KHSRP | soft tissue 1; peripheral nerve[High] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NUDT21 | CPSF6 | 1.0 | 0.892 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM boldt youn_WMM hein () Malo bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM |
| NUDT21 | KHSRP | 0.974 | 0.786 | hein_WMM bioplex_WMM Guru bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| CPSF6 | KHSRP | 0.812 | 0.696 | bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM |
Related Complexes