hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_06481.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PEX7 | Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7) | 5 | UniProt NCBI |
| ACAA1 | 3-ketoacyl-CoA thiolase, peroxisomal (EC 2.3.1.16) (Acetyl-CoA C-myristoyltransferase) (EC 2.3.1.155) (Acetyl-CoA acyltransferase) (EC 2.3.1.9) (Beta-ketothiolase) (Peroxisomal 3-oxoacyl-CoA thiolase) | 5 | UniProt NCBI |
| PEX13 | Peroxisomal membrane protein PEX13 (Peroxin-13) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04146 | 2.17649206055e-06 | 1.0 | PEX7 ACAA1 PEX13 | Peroxisome |
| REAC:R-HSA-9033241 | 8.07035063329e-06 | 1.0 | PEX7 ACAA1 PEX13 | Peroxisomal protein import |
| REAC:R-HSA-9609507 | 0.000191325541956 | 1.0 | PEX7 ACAA1 PEX13 | Protein localization |
| HP:0010571 | 0.00115089028102 | 0.666666666667 | PEX7 PEX13 | Elevated circulating phytanic acid concentration |
| HP:0010965 | 0.00115089028102 | 0.666666666667 | PEX7 PEX13 | Abnormal circulating phytanic acid concentration |
| HP:0010964 | 0.00151751896202 | 0.666666666667 | PEX7 PEX13 | Abnormal circulating long-chain fatty-acid concentration |
| HP:0010655 | 0.00626783027637 | 0.666666666667 | PEX7 PEX13 | Epiphyseal stippling |
| HP:0004359 | 0.0154672949612 | 0.666666666667 | PEX7 PEX13 | Abnormal circulating fatty-acid concentration |
| GO:0005777 | 0.0185434783245 | 1.0 | PEX7 ACAA1 PEX13 | peroxisome |
| GO:0042579 | 0.0185434783245 | 1.0 | PEX7 ACAA1 PEX13 | microbody |
| HP:0010656 | 0.023094623718 | 0.666666666667 | PEX7 PEX13 | Abnormal epiphyseal ossification |
| HPA:0091003 | 0.0235249667108 | 0.666666666667 | PEX13 ACAA1 | cerebellum; molecular layer cells - cytoplasm/membrane[High] |
| HPA:0090922 | 0.0244321680476 | 0.666666666667 | PEX13 ACAA1 | cerebellum; GLUC cells - cytoplasm/membrane[>=Medium] |
| WP:WP1941 | 0.0248274760036 | 0.333333333333 | ACAA1 | Peroxisomal beta oxidation of tetracosanoyl CoA |
| HPA:0090943 | 0.026615200214 | 0.666666666667 | PEX13 ACAA1 | cerebellum; Purkinje cells - cytoplasm/membrane[High] |
| HPA:0090921 | 0.0292235343026 | 0.666666666667 | PEX13 ACAA1 | cerebellum; GLUC cells - cytoplasm/membrane[>=Low] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PEX7 | PEX13 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ACAA1 | PEX7 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ACAA1 | PEX13 | 0.027 | 0.11 | bioplex3_WMM WMM_only |
Related Complexes