hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_06499.1
Complex Portal: CPX-15674
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PHF11 | PHD finger protein 11 (BRCA1 C-terminus-associated protein) (Renal carcinoma antigen NY-REN-34) | 5 | UniProt NCBI |
| C5 | Complement C5 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4) [Cleaved into: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain] | 5 | UniProt NCBI |
| PYCARD | Apoptosis-associated speck-like protein containing a CARD (hASC) (Caspase recruitment domain-containing protein 5) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1) | 5 | UniProt NCBI |
| ANKRD22 | Ankyrin repeat domain-containing protein 22 | 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:05133 | 0.00426927356048 | 0.5 | C5 PYCARD | Pertussis |
| CORUM:6323 | 0.049938562206 | 0.25 | PYCARD | NLRP3 inflammasome |
| CORUM:6324 | 0.049938562206 | 0.25 | PYCARD | NLRP2 inflammasome |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| C5 | PHF11 | 0.998 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ANKRD22 | PHF11 | 0.995 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PYCARD | PHF11 | 0.992 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PYCARD | ANKRD22 | 0.901 | bioplex_WMM bioplex3_WMM WMM_only | ||
| C5 | ANKRD22 | 0.634 | bioplex3_WMM WMM_only | ||
| C5 | PYCARD | 0.362 | 0.072 | bioplex3_WMM WMM_only |
Related Complexes