hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06524.1
Complex Portal: CPX-17699
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PADI2 | Protein-arginine deiminase type-2 (EC 3.5.3.15) (PAD-H19) (Peptidylarginine deiminase II) (Protein-arginine deiminase type II) | 5 | UniProt NCBI |
| APOL1 | Apolipoprotein L1 (Apolipoprotein L) (Apo-L) (ApoL) (Apolipoprotein L-I) (ApoL-I) | 5 | UniProt NCBI |
| DYSF | Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1) | 5 | UniProt NCBI |
| NCF2 | Neutrophil cytosol factor 2 (NCF-2) (67 kDa neutrophil oxidase factor) (NADPH oxidase activator 2) (Neutrophil NADPH oxidase factor 2) (p67-phox) | 5 | UniProt NCBI |
| APOC1 | Apolipoprotein C-I (Apo-CI) (ApoC-I) (Apolipoprotein C1) [Cleaved into: Truncated apolipoprotein C-I] | 5 | UniProt NCBI |
| KLK10 | Kallikrein-10 (EC 3.4.21.-) (Normal epithelial cell-specific 1) (Protease serine-like 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0640411 | 0.0034980693017 | 0.333333333333 | NCF2 DYSF | endometrium; macrophages[>=Low] |
| HPA:0640412 | 0.0034980693017 | 0.333333333333 | NCF2 DYSF | endometrium; macrophages[>=Medium] |
| HPA:0640203 | 0.00381537880503 | 0.333333333333 | NCF2 DYSF | endometrium; endothelial cells[High] |
| HPA:0640202 | 0.00820867416539 | 0.333333333333 | NCF2 DYSF | endometrium; endothelial cells[>=Medium] |
| HPA:0640201 | 0.0091848403014 | 0.333333333333 | NCF2 DYSF | endometrium; endothelial cells[>=Low] |
| HPA:0641531 | 0.0102154360236 | 0.333333333333 | NCF2 DYSF | endometrium; stromal fibroblasts[>=Low] |
| HPA:0640691 | 0.0175386683177 | 0.333333333333 | NCF2 DYSF | endometrium; smooth muscle cells[>=Low] |
| HPA:0641502 | 0.0182368818217 | 0.333333333333 | NCF2 DYSF | endometrium; ciliated epithelial cells[>=Medium] |
| HPA:0641501 | 0.0268062509233 | 0.333333333333 | NCF2 DYSF | endometrium; ciliated epithelial cells[>=Low] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| APOL1 | KLK10 | 0.989 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| APOC1 | KLK10 | 0.989 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| DYSF | KLK10 | 0.984 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PADI2 | KLK10 | 0.977 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| NCF2 | KLK10 | 0.962 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| APOL1 | DYSF | 0.902 | 0.110115942029 | bioplex3_WMM WMM_only | |
| APOL1 | NCF2 | 0.902 | bioplex3_WMM WMM_only | ||
| DYSF | APOC1 | 0.902 | bioplex3_WMM WMM_only | ||
| DYSF | NCF2 | 0.902 | 0.07 | bioplex3_WMM WMM_only | |
| NCF2 | APOC1 | 0.902 | bioplex3_WMM WMM_only | ||
| APOL1 | APOC1 | 0.902 | bioplex3_WMM WMM_only | ||
| PADI2 | APOL1 | 0.902 | bioplex3_WMM WMM_only | ||
| PADI2 | DYSF | 0.902 | 0.096 | bioplex3_WMM WMM_only | |
| PADI2 | APOC1 | 0.902 | bioplex3_WMM WMM_only | ||
| PADI2 | NCF2 | 0.902 | 0.132 | bioplex3_WMM WMM_only |
Related Complexes