hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_06535.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PBX3 | Pre-B-cell leukemia transcription factor 3 (Homeobox protein PBX3) | 5 | UniProt NCBI |
| PBX1 | Pre-B-cell leukemia transcription factor 1 (Homeobox protein PBX1) (Homeobox protein PRL) | 5 | UniProt NCBI |
| PKNOX2 | Homeobox protein PKNOX2 (Homeobox protein PREP-2) (PBX/knotted homeobox 2) | 5 | UniProt NCBI |
| PBX2 | Pre-B-cell leukemia transcription factor 2 (Homeobox protein PBX2) (Protein G17) | 5 | UniProt NCBI |
| PKNOX1 | Homeobox protein PKNOX1 (Homeobox protein PREP-1) (PBX/knotted homeobox 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0131331 | 0.0191811519078 | 0.6 | PBX3 PKNOX2 PBX1 | colon; mucosal lymphoid cells[>=Low] |
| GO:0000978 | 0.0192772113985 | 1.0 | PBX3 PKNOX1 PBX2 PKNOX2 PBX1 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| HPA:0131301 | 0.0205763648033 | 0.6 | PBX3 PKNOX2 PBX1 | colon; enterocytes[>=Low] |
| GO:0000987 | 0.0213878677719 | 1.0 | PBX3 PKNOX1 PBX2 PKNOX2 PBX1 | cis-regulatory region sequence-specific DNA binding |
| HPA:0401331 | 0.0241927281198 | 0.6 | PBX3 PKNOX2 PBX1 | rectum; mucosal lymphoid cells[>=Low] |
| GO:0000981 | 0.0378314216665 | 1.0 | PBX3 PKNOX1 PBX2 PKNOX2 PBX1 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| WP:WP2853 | 0.0379631029161 | 0.4 | PBX3 PBX1 | Endoderm differentiation |
| WP:WP706 | 0.0420114386662 | 0.4 | PBX1 PKNOX1 | Sudden infant death syndrome SIDS susceptibility pathways |
| GO:0000977 | 0.0435745197674 | 1.0 | PBX3 PKNOX1 PBX2 PKNOX2 PBX1 | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| WP:WP2857 | 0.0462612174005 | 0.4 | PBX3 PBX1 | Mesodermal commitment pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PKNOX1 | PBX1 | 0.996 | 0.222 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| PKNOX1 | PBX2 | 0.995 | 0.242 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| PBX2 | PKNOX2 | 0.992 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| PBX3 | PKNOX2 | 0.988 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| PBX1 | PBX2 | 0.982 | 0.246 | bioplex_WMM bioplex3_WMM youn_WMM fraction |
| PBX3 | PBX2 | 0.977 | 0.182 | bioplex_WMM bioplex3_WMM WMM_only |
| PBX1 | PBX3 | 0.976 | 0.142 | bioplex_WMM bioplex3_WMM WMM_only |
| PBX1 | PKNOX2 | 0.971 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| PKNOX1 | PKNOX2 | 0.558 | bioplex_WMM bioplex3_WMM WMM_only | |
| PKNOX1 | PBX3 | 0.226 | 0.14 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes