hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06544.1
Confidence: Very High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
FAM241A | Uncharacterized protein FAM241A | 2 | UniProt   NCBI |
TMEM208 | Transmembrane protein 208 | 5 | UniProt   NCBI |
PRAF2 | PRA1 family protein 2 | 5 | UniProt   NCBI |
SCAMP4 | Secretory carrier-associated membrane protein 4 (Secretory carrier membrane protein 4) | 5 | UniProt   NCBI |
TMEM170A | Transmembrane protein 170A | 5 | UniProt   NCBI |
REEP6 | Receptor expression-enhancing protein 6 (Polyposis locus protein 1-like 1) | 5 | UniProt   NCBI |
RABAC1 | Prenylated Rab acceptor protein 1 (PRA1 family protein 1) | 5 | UniProt   NCBI |
TMEM68 | DGAT1/2-independent enzyme synthesizing storage lipids (DIESL) (EC 2.3.1.-) (2-acylglycerol/1,2-diacylglycerol O-acyltransferase) (Monoacylglycerol/Diacylglycerol O-acyltransferase) (MGAT/DGAT) (EC 2.3.1.20, EC 2.3.1.22) (Transmembrane protein 68) | 5 | UniProt   NCBI |
ARL6IP1 | ADP-ribosylation factor-like protein 6-interacting protein 1 (ARL-6-interacting protein 1) (Aip-1) (Apoptotic regulator in the membrane of the endoplasmic reticulum) | 5 | UniProt   NCBI |
REEP5 | Receptor expression-enhancing protein 5 (Polyposis locus protein 1) (Protein TB2) | 5 | UniProt   NCBI |
RTN3 | Reticulon-3 (Homolog of ASY protein) (HAP) (Neuroendocrine-specific protein-like 2) (NSP-like protein 2) (Neuroendocrine-specific protein-like II) (NSP-like protein II) (NSPLII) | 5 | UniProt   NCBI |
TMEM128 | Transmembrane protein 128 | 5 | UniProt   NCBI |
FAM241B | Protein FAM241B | 5 | UniProt   NCBI |
HSD17B2 | 17-beta-hydroxysteroid dehydrogenase type 2 (17-beta-HSD 2) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Estradiol 17-beta-dehydrogenase 2) (EC 1.1.1.62) (Microsomal 17-beta-hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 9C member 2) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.239) | 5 | UniProt   NCBI |
RNFT1 | E3 ubiquitin-protein ligase RNFT1 (EC 2.3.2.27) (Protein PTD016) (RING finger and transmembrane domain-containing protein 1) | 5 | UniProt   NCBI |
RTN1 | Reticulon-1 (Neuroendocrine-specific protein) | 5 | UniProt   NCBI |
PILRB | Paired immunoglobulin-like type 2 receptor beta (Activating receptor PILR-beta) (Cell surface receptor FDFACT) | 4 | UniProt   NCBI |
FAM210B | Protein FAM210B, mitochondrial | 5 | UniProt   NCBI |
RTN2 | Reticulon-2 (Neuroendocrine-specific protein-like 1) (NSP-like protein 1) (Neuroendocrine-specific protein-like I) (NSP-like protein I) (NSPLI) | 5 | UniProt   NCBI |
MOG | Myelin-oligodendrocyte glycoprotein | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  GO:0007029 | 3.75174418048e-05 | 0.3 | ARL6IP1 RTN3 RTN1 REEP5 TMEM170A REEP6 | endoplasmic reticulum organization |
  GO:0071786 | 0.000609061014292 | 0.2 | RTN1 RTN3 TMEM170A ARL6IP1 | endoplasmic reticulum tubular network organization |
  GO:0071787 | 0.00109385703544 | 0.15 | RTN1 ARL6IP1 RTN3 | endoplasmic reticulum tubular network formation |
  HPA:0481302 | 0.0189967449189 | 0.25 | HSD17B2 REEP5 REEP6 MOG RABAC1 | small intestine; enterocytes[>=Medium] |
  HPA:0481303 | 0.0275988617485 | 0.2 | HSD17B2 REEP5 REEP6 RABAC1 | small intestine; enterocytes[High] |
  GO:1902430 | 0.0310665990836 | 0.15 | RTN1 RTN3 RTN2 | negative regulation of amyloid-beta formation |
  GO:1902992 | 0.0493379236969 | 0.15 | RTN1 RTN3 RTN2 | negative regulation of amyloid precursor protein catabolic process |
  HPA:0481293 | 0.0499221732978 | 0.2 | HSD17B2 REEP5 REEP6 RABAC1 | small intestine; endocrine cells[High] |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD |
---|---|---|---|
 REEP6 |  REEP5 | 1.0 |            |
 REEP5 |  PRAF2 | 0.999 | 0.096           |
 REEP5 |  FAM241B | 0.999 | 0.082           |
 FAM210B |  REEP5 | 0.999 | 0.134           |
 REEP5 |  RABAC1 | 0.999 | 0.104           |
 REEP6 |  FAM241A | 0.998 |            |
 REEP5 |  FAM241A | 0.998 | 0.148           |
 REEP5 |  SCAMP4 | 0.998 | 0.03           |
 FAM241A |  RTN2 | 0.998 | 0.054           |
 TMEM68 |  REEP5 | 0.998 | 0.206           |
 RTN1 |  RTN2 | 0.998 | 0.102           |
 REEP5 |  TMEM208 | 0.997 | 0.14           |
 REEP6 |  TMEM208 | 0.997 |            |
 RTN3 |  FAM241A | 0.996 | 0.064           |
 FAM241B |  FAM241A | 0.995 | 0.062           |
 FAM241B |  TMEM208 | 0.995 | 0.086           |
 RTN3 |  TMEM208 | 0.993 | 0.14           |
 RNFT1 |  REEP5 | 0.993 | 0.106           |
 REEP6 |  RTN3 | 0.991 |            |
 RTN3 |  RTN2 | 0.988 | 0.1           |
 TMEM128 |  REEP6 | 0.987 |            |
 PILRB |  FAM241A | 0.987 |            |
 RTN3 |  FAM241B | 0.986 | 0.1           |
 RTN1 |  FAM241A | 0.986 | 0.13           |
 TMEM128 |  REEP5 | 0.986 | 0.052           |
 RTN3 |  ARL6IP1 | 0.981 | 0.088           |
 REEP6 |  SCAMP4 | 0.979 |            |
 TMEM128 |  TMEM208 | 0.977 | 0.122           |
 TMEM128 |  RTN2 | 0.974 | 0.076           |
 RTN3 |  RABAC1 | 0.974 | 0.15           |
 RTN3 |  TMEM170A | 0.974 |            |
 TMEM170A |  FAM241A | 0.974 |            |
 MOG |  FAM241A | 0.974 |            |
 RTN3 |  MOG | 0.973 |            |
 FAM210B |  PRAF2 | 0.972 | 0.08           |
 FAM210B |  FAM241A | 0.972 | 0.094           |
 RNFT1 |  REEP6 | 0.971 |            |
 TMEM68 |  RTN3 | 0.97 | 0.076           |
 RABAC1 |  FAM241A | 0.969 | 0.054           |
 RTN1 |  RTN3 | 0.969 | 0.276           |
 REEP5 |  TMEM170A | 0.967 |            |
 REEP5 |  PILRB | 0.967 |            |
 RTN3 |  PILRB | 0.966 |            |
 REEP6 |  TMEM170A | 0.964 |            |
 REEP6 |  HSD17B2 | 0.964 |            |
 REEP6 |  FAM241B | 0.962 |            |
 REEP6 |  MOG | 0.961 |            |
 REEP6 |  PILRB | 0.961 |            |
 HSD17B2 |  REEP5 | 0.96 | 0.074           |
 REEP6 |  FAM210B | 0.96 |            |
 FAM241A |  ARL6IP1 | 0.96 | 0.068           |
 REEP5 |  RTN2 | 0.959 | 0.04           |
 REEP6 |  RTN2 | 0.958 |            |
 ARL6IP1 |  RTN2 | 0.958 | 0.046           |
 REEP6 |  TMEM68 | 0.957 |            |
 REEP5 |  MOG | 0.957 |            |
 FAM241B |  RTN2 | 0.953 | 0.048           |
 FAM241A |  PRAF2 | 0.942 | 0.046           |
 TMEM128 |  RABAC1 | 0.94 | 0.096           |
 RABAC1 |  RTN2 | 0.938 | 0.064           |
 RTN1 |  FAM210B | 0.937 | 0.07           |
 TMEM208 |  FAM241A | 0.932 | 0.074           |
 FAM241B |  TMEM170A | 0.927 |            |
 REEP5 |  RTN3 | 0.92 | 0.182           |
 FAM241B |  PILRB | 0.919 |            |
 RABAC1 |  TMEM208 | 0.914 | 0.186           |
 FAM210B |  FAM241B | 0.911 | 0.076           |
 RTN1 |  ARL6IP1 | 0.896 | 0.158           |
 TMEM128 |  RTN3 | 0.894 | 0.13           |
 RABAC1 |  ARL6IP1 | 0.893 | 0.186           |
 FAM210B |  RTN2 | 0.886 | 0.076           |
 TMEM128 |  FAM241B | 0.869 | 0.092           |
 RTN1 |  RABAC1 | 0.864 | 0.03           |
 REEP6 |  PRAF2 | 0.811 |            |
 TMEM68 |  ARL6IP1 | 0.81 | 0.148           |
 RNFT1 |  SCAMP4 | 0.808 | 0.066           |
 FAM210B |  RABAC1 | 0.805 | 0.116           |
 TMEM68 |  RTN2 | 0.787 | 0.05           |
 FAM241B |  PRAF2 | 0.784 | 0.058           |
 TMEM68 |  FAM210B | 0.771 | 0.146           |
 RABAC1 |  PRAF2 | 0.771 | 0.108           |
 RNFT1 |  FAM241B | 0.766 | 0.062           |
 SCAMP4 |  FAM241B | 0.76 | 0.044           |
 RNFT1 |  FAM210B | 0.757 | 0.11           |
 TMEM68 |  PRAF2 | 0.744 | 0.116           |
 TMEM68 |  FAM241B | 0.74 | 0.082           |
 SCAMP4 |  TMEM208 | 0.73 | 0.08           |
 TMEM68 |  SCAMP4 | 0.726 | 0.068           |
 REEP6 |  ARL6IP1 | 0.717 |            |
 FAM210B |  SCAMP4 | 0.709 | 0.07           |
 SCAMP4 |  RABAC1 | 0.701 | 0.152           |
 FAM241B |  ARL6IP1 | 0.7 | 0.052           |
 SCAMP4 |  PRAF2 | 0.696 | 0.034           |
 SCAMP4 |  FAM241A | 0.68 | 0.066           |
 TMEM68 |  FAM241A | 0.68 | 0.142           |
 RNFT1 |  TMEM68 | 0.677 | 0.056           |
 REEP6 |  RABAC1 | 0.675 |            |
 TMEM68 |  RABAC1 | 0.659 | 0.116           |
 RNFT1 |  FAM241A | 0.656 | 0.148           |
 FAM241B |  RABAC1 | 0.621 | 0.11           |
 TMEM208 |  PRAF2 | 0.613 | 0.05           |
 RTN1 |  TMEM68 | 0.533 | 0.084           |
 RTN1 |  TMEM128 | 0.521 | 0.094           |
 TMEM68 |  TMEM208 | 0.518 | 0.048           |
 RTN1 |  REEP6 | 0.506 |            |
 RNFT1 |  RABAC1 | 0.481 | 0.166           |
 RNFT1 |  PRAF2 | 0.474 | 0.04           |
 ARL6IP1 |  PRAF2 | 0.405 | 0.068           |
 FAM210B |  ARL6IP1 | 0.371 | 0.056           |
 RNFT1 |  TMEM208 | 0.364 | 0.096           |
 REEP5 |  ARL6IP1 | 0.348 | 0.138           |
 FAM210B |  TMEM208 | 0.345 | 0.074           |
 RTN3 |  PRAF2 | 0.322 | 0.084           |
 PRAF2 |  RTN2 | 0.289 | 0.044           |
 RTN1 |  FAM241B | 0.212 | 0.104           |
 RTN1 |  TMEM208 | 0.198 | 0.078           |
 TMEM208 |  RTN2 | 0.17 | 0.048           |
 TMEM208 |  ARL6IP1 | 0.152 | 0.0728888888889           |
 FAM210B |  RTN3 | 0.139 | 0.098           |
 RNFT1 |  RTN2 | 0.108 | 0.056           |
 RTN1 |  REEP5 | 0.084 | 0.168           |
 SCAMP4 |  ARL6IP1 | 0.076 | 0.06           |
 RTN1 |  PRAF2 | 0.036 | 0.048           |
 TMEM128 |  ARL6IP1 | 0.024 | 0.13           |
 RNFT1 |  RTN3 | 0.023 | 0.09           |
 TMEM128 |  PRAF2 | 0.022 | 0.056           |
 TMEM128 |  TMEM68 | 0.02 | 0.17           |
 TMEM128 |  FAM241A | 0.019 | 0.108           |
 RTN1 |  SCAMP4 | 0.016 | 0.034           |
 SCAMP4 |  RTN3 | 0.006 | 0.072           |
Related Complexes