hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06556.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| H2BC26 | Histone H2B type 3-B (H2B type 12) (H2B-clustered histone 26) (H2B.U histone 1) | 5 | UniProt NCBI |
| ZNHIT1 | Zinc finger HIT domain-containing protein 1 (Cyclin-G1-binding protein 1) (Zinc finger protein subfamily 4A member 1) (p18 Hamlet) | 5 | UniProt NCBI |
| SRCAP | Helicase SRCAP (EC 3.6.4.-) (Domino homolog 2) (Snf2-related CBP activator) | 5 | UniProt NCBI |
| RBP1 | Retinol-binding protein 1 (Cellular retinol-binding protein) (CRBP) (Cellular retinol-binding protein I) (CRBP-I) | 5 | UniProt NCBI |
| CFDP1 | Craniofacial development protein 1 (Bucentaur) | 4 | UniProt NCBI |
| ANP32E | Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP-like protein) (LANP-L) | 5 | UniProt NCBI |
| BAHD1 | Bromo adjacent homology domain-containing 1 protein (BAH domain-containing protein 1) | 5 | UniProt NCBI |
| H2AZ1 | Histone H2A.Z (H2A/z) | 5 | UniProt NCBI |
| H2BC1 | Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:304 | 1.56948544187e-06 | 0.333333333333 | H2AZ1 ZNHIT1 SRCAP | SRCAP-associated chromatin remodeling complex |
| GO:0000812 | 2.3646695756e-06 | 0.444444444444 | CFDP1 ANP32E ZNHIT1 SRCAP | Swr1 complex |
| GO:0097346 | 5.78196693602e-05 | 0.444444444444 | CFDP1 ANP32E ZNHIT1 SRCAP | INO80-type complex |
| KEGG:03082 | 0.00144106213769 | 0.333333333333 | H2AZ1 ZNHIT1 SRCAP | ATP-dependent chromatin remodeling |
| KEGG:05322 | 0.00161357227069 | 0.333333333333 | H2BC1 H2BC26 H2AZ1 | Systemic lupus erythematosus |
| GO:0000118 | 0.0020721506318 | 0.444444444444 | CFDP1 ANP32E ZNHIT1 SRCAP | histone deacetylase complex |
| GO:0006325 | 0.00341845413627 | 0.666666666667 | H2BC1 SRCAP H2AZ1 BAHD1 CFDP1 ZNHIT1 | chromatin organization |
| KEGG:04613 | 0.00421630879124 | 0.333333333333 | H2BC1 H2BC26 H2AZ1 | Neutrophil extracellular trap formation |
| KEGG:05034 | 0.00421630879124 | 0.333333333333 | H2BC1 H2BC26 H2AZ1 | Alcoholism |
| GO:0000786 | 0.00487995873933 | 0.444444444444 | H2AZ1 ZNHIT1 H2BC1 SRCAP | nucleosome |
| REAC:R-HSA-977225 | 0.00514835022343 | 0.333333333333 | H2BC1 H2BC26 H2AZ1 | Amyloid fiber formation |
| GO:0071824 | 0.00818347254642 | 0.666666666667 | H2BC1 SRCAP H2AZ1 BAHD1 CFDP1 ZNHIT1 | protein-DNA complex organization |
| GO:0070603 | 0.0090427452869 | 0.444444444444 | CFDP1 ANP32E ZNHIT1 SRCAP | SWI/SNF superfamily-type complex |
| HPA:0500703 | 0.0351784090028 | 0.333333333333 | H2AZ1 H2BC26 CFDP1 | soft tissue 1; peripheral nerve[High] |
| GO:1904949 | 0.0475745494854 | 0.444444444444 | CFDP1 ANP32E ZNHIT1 SRCAP | ATPase complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| ZNHIT1 | SRCAP | 0.999 | 0.148 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| H2BC1 | SRCAP | 0.999 | 0.274 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| H2BC1 | ZNHIT1 | 0.999 | 0.352 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| H2AZ1 | SRCAP | 0.998 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| H2AZ1 | ZNHIT1 | 0.998 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| H2BC1 | CFDP1 | 0.998 | 0.138 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| H2AZ1 | BAHD1 | 0.998 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| H2BC26 | ANP32E | 0.998 | 0.152 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| H2BC1 | BAHD1 | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| H2BC26 | ZNHIT1 | 0.997 | 0.294 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| H2BC26 | SRCAP | 0.997 | 0.25 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| H2BC1 | ANP32E | 0.996 | 0.234 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| H2BC26 | CFDP1 | 0.995 | 0.214820512821 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| H2BC26 | H2AZ1 | 0.994 | bioplex3_HEK293 bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| H2BC1 | H2AZ1 | 0.989 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM | |
| H2BC26 | BAHD1 | 0.968 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| SRCAP | ANP32E | 0.964 | 0.038 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only boldt_WMM |
| BAHD1 | SRCAP | 0.964 | bioplex_WMM bioplex3_WMM WMM_only | |
| BAHD1 | ZNHIT1 | 0.964 | bioplex_WMM bioplex3_WMM WMM_only | |
| H2BC26 | RBP1 | 0.951 | 0.092 | bioplex3_HEK293 bioplex3_WMM WMM_only |
| BAHD1 | ANP32E | 0.938 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| CFDP1 | ZNHIT1 | 0.926 | 0.056 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| H2AZ1 | ANP32E | 0.921 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM WMM_only | |
| CFDP1 | SRCAP | 0.901 | 0.014 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| ZNHIT1 | ANP32E | 0.88 | 0.128 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| CFDP1 | BAHD1 | 0.747 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| CFDP1 | ANP32E | 0.745 | 0.05 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| CFDP1 | H2AZ1 | 0.19 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| RBP1 | SRCAP | 0.099 | 0.032 | bioplex3_WMM WMM_only |
| RBP1 | ANP32E | 0.083 | 0.056 | bioplex_WMM bioplex3_WMM WMM_only |
| RBP1 | CFDP1 | 0.076 | 0.024 | bioplex3_WMM WMM_only |
| RBP1 | BAHD1 | 0.065 | bioplex3_WMM WMM_only | |
| RBP1 | ZNHIT1 | 0.036 | 0.07 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| RBP1 | H2AZ1 | 0.017 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| H2BC1 | RBP1 | 0.005 | 0.206 | bioplex3_HCT116 WMM_only |
Related Complexes