hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06558.1
Complex Portal: CPX-25158
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| STEAP4 | Metalloreductase STEAP4 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 4) (SixTransMembrane protein of prostate 2) (Tumor necrosis factor, alpha-induced protein 9) | 5 | UniProt NCBI |
| ITGB2 | Integrin beta-2 (Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD antigen CD18) | 5 | UniProt NCBI |
| MMP12 | Macrophage metalloelastase (MME) (EC 3.4.24.65) (Macrophage elastase) (ME) (hME) (Matrix metalloproteinase-12) (MMP-12) | 5 | UniProt NCBI |
| SARAF | Store-operated calcium entry-associated regulatory factor (SARAF) (SOCE-associated regulatory factor) (HBV X-transactivated gene 3 protein) (HBV XAg-transactivated protein 3) (Protein FOAP-7) (Transmembrane protein 66) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2153 | 0.049938562206 | 0.25 | ITGB2 | ITGAM-ITGB2-CD11 complex |
| CORUM:7013 | 0.049938562206 | 0.25 | ITGB2 | ITGB2-RACK1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MMP12 | SARAF | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| STEAP4 | SARAF | 0.987 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ITGB2 | SARAF | 0.97 | 0.062 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| STEAP4 | MMP12 | 0.902 | bioplex3_WMM WMM_only | ||
| ITGB2 | MMP12 | 0.902 | bioplex3_WMM WMM_only | ||
| STEAP4 | ITGB2 | 0.626 | 0.144 | bioplex3_WMM WMM_only |
Related Complexes