hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06590.1
Complex Portal: CPX-17469
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MUL1 | Mitochondrial ubiquitin ligase activator of NFKB 1 (EC 2.3.2.27) (E3 SUMO-protein ligase MUL1) (E3 ubiquitin-protein ligase MUL1) (Growth inhibition and death E3 ligase) (Mitochondrial-anchored protein ligase) (Protein Hades) (Putative NF-kappa-B-activating protein 266) (RING finger protein 218) (RING-type E3 ubiquitin transferase NFKB 1) | 5 | UniProt NCBI |
| FAR2 | Fatty acyl-CoA reductase 2 (EC 1.2.1.84) (Male sterility domain-containing protein 1) | 5 | UniProt NCBI |
| PEX19 | Peroxisomal biogenesis factor 19 (33 kDa housekeeping protein) (Peroxin-19) (Peroxisomal farnesylated protein) | 5 | UniProt NCBI |
| MGAT2 | Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (EC 2.4.1.143) (Beta-1,2-N-acetylglucosaminyltransferase II) (GlcNAc-T II) (GNT-II) (Mannoside acetylglucosaminyltransferase 2) (N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II) | 5 | UniProt NCBI |
| MTARC2 | Mitochondrial amidoxime reducing component 2 (mARC2) (EC 1.7.-.-) (Molybdenum cofactor sulfurase C-terminal domain-containing protein 2) (MOSC domain-containing protein 2) (Moco sulfurase C-terminal domain-containing protein 2) | 5 | UniProt NCBI |
| MOSPD2 | Motile sperm domain-containing protein 2 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5275 | 0.00136659658622 | 0.333333333333 | FAR2 PEX19 | Ether lipid biosynthesis |
| KEGG:04146 | 0.0144916673313 | 0.333333333333 | FAR2 PEX19 | Peroxisome |
| GO:0098588 | 0.046464555054 | 1.0 | MTARC2 MOSPD2 PEX19 MGAT2 FAR2 MUL1 | bounding membrane of organelle |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| FAR2 | PEX19 | 0.997 | 0.068 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| PEX19 | MUL1 | 0.997 | 0.096 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| PEX19 | MOSPD2 | 0.994 | 0.034 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| MTARC2 | PEX19 | 0.992 | 0.058 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| MGAT2 | PEX19 | 0.975 | 0.062 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| FAR2 | MTARC2 | 0.949 | 0.062 | bioplex_WMM bioplex3_WMM WMM_only | |
| MTARC2 | MOSPD2 | 0.885 | 0.096 | bioplex_WMM bioplex3_WMM WMM_only | |
| FAR2 | MUL1 | 0.862 | 0.076 | bioplex_WMM bioplex3_WMM WMM_only | |
| MGAT2 | MTARC2 | 0.859 | 0.078 | bioplex_WMM bioplex3_WMM WMM_only | |
| MTARC2 | MUL1 | 0.846 | 0.12 | bioplex_WMM bioplex3_WMM WMM_only | |
| FAR2 | MOSPD2 | 0.614 | 0.068 | bioplex_WMM bioplex3_WMM WMM_only | |
| MGAT2 | MUL1 | 0.528 | 0.084 | bioplex_WMM bioplex3_WMM WMM_only | |
| MGAT2 | MOSPD2 | 0.28 | 0.024 | bioplex_WMM bioplex3_WMM WMM_only | |
| MUL1 | MOSPD2 | 0.261 | 0.08 | bioplex_WMM bioplex3_WMM WMM_only | |
| MGAT2 | FAR2 | 0.21 | 0.1 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes