hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06609.1
Complex Portal: CPX-19524
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SCAF8 | SR-related and CTD-associated factor 8 (CDC5L complex-associated protein 7) (RNA-binding motif protein 16) | 5 | UniProt NCBI |
| RBM17 | Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17) | 5 | UniProt NCBI |
| U2SURP | U2 snRNP-associated SURP motif-containing protein (140 kDa Ser/Arg-rich domain protein) (U2-associated protein SR140) | 5 | UniProt NCBI |
| CHERP | Calcium homeostasis endoplasmic reticulum protein (ERPROT 213-21) (SR-related CTD-associated factor 6) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2755 | 2.84457331044e-06 | 0.75 | RBM17 CHERP U2SURP | 17S U2 snRNP |
| KEGG:03040 | 0.000108396031683 | 0.75 | RBM17 CHERP U2SURP | Spliceosome |
| REAC:R-HSA-72163 | 0.00185188916926 | 0.75 | RBM17 CHERP U2SURP | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 0.002052480752 | 0.75 | RBM17 CHERP U2SURP | mRNA Splicing |
| REAC:R-HSA-72203 | 0.00469213914253 | 0.75 | RBM17 CHERP U2SURP | Processing of Capped Intron-Containing Pre-mRNA |
| HPA:0301363 | 0.0101307410249 | 0.75 | RBM17 SCAF8 U2SURP | lung; alveolar cells type I[High] |
| HPA:0250123 | 0.011326451641 | 0.75 | RBM17 SCAF8 U2SURP | hippocampus; glial cells[High] |
| HPA:0301373 | 0.023257212468 | 0.75 | RBM17 SCAF8 U2SURP | lung; alveolar cells type II[High] |
| HPA:0461493 | 0.0366507731727 | 0.5 | RBM17 U2SURP | skin 1; vascular mural cells[High] |
| HPA:0300201 | 0.0401447172992 | 0.75 | RBM17 SCAF8 U2SURP | lung; endothelial cells[>=Low] |
| HPA:0050093 | 0.0447503600593 | 0.75 | RBM17 SCAF8 U2SURP | breast; myoepithelial cells[High] |
| CORUM:351 | 0.047170241778 | 0.5 | RBM17 U2SURP | Spliceosome |
| HPA:0510113 | 0.0499490020628 | 0.5 | RBM17 U2SURP | soft tissue 2; chondrocytes[High] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RBM17 | CHERP | 1.0 | 0.908 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM | |
| RBM17 | U2SURP | 1.0 | 0.888 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM treiber_WMM | |
| U2SURP | CHERP | 0.999 | 0.956 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM | |
| RBM17 | SCAF8 | 0.962 | 0.256 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction | |
| SCAF8 | CHERP | 0.953 | 0.52 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction | |
| SCAF8 | U2SURP | 0.937 | 0.408 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes