hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06614.1
Complex Portal: CPX-15787
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FBXW4 | F-box/WD repeat-containing protein 4 (Dactylin) (F-box and WD-40 domain-containing protein 4) | 4 | UniProt NCBI |
| PFDN5 | Prefoldin subunit 5 (Myc modulator 1) (c-Myc-binding protein Mm-1) | 5 | UniProt NCBI |
| VBP1 | Prefoldin subunit 3 (HIBBJ46) (von Hippel-Lindau-binding protein 1) (VBP-1) (VHL-binding protein 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4918 | 1.69880545178e-05 | 0.666666666667 | PFDN5 VBP1 | Cellular proteostasis |
| REAC:R-HSA-390466 | 4.60862934812e-05 | 1.0 | FBXW4 VBP1 PFDN5 | Chaperonin-mediated protein folding |
| CORUM:33 | 5.12534978153e-05 | 0.666666666667 | PFDN5 VBP1 | Prefoldin complex |
| CORUM:112 | 5.12534978153e-05 | 0.666666666667 | PFDN5 VBP1 | Prefoldin complex |
| REAC:R-HSA-391251 | 5.85958968853e-05 | 1.0 | FBXW4 VBP1 PFDN5 | Protein folding |
| REAC:R-HSA-389957 | 0.00239054881557 | 0.666666666667 | PFDN5 VBP1 | Prefoldin mediated transfer of substrate to CCT/TriC |
| REAC:R-HSA-389958 | 0.0033773260227 | 0.666666666667 | PFDN5 VBP1 | Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding |
| GO:0016272 | 0.0210651876021 | 0.666666666667 | PFDN5 VBP1 | prefoldin complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PFDN5 | VBP1 | 1.0 | 0.866 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 gupta_WMM fraction boldt_WMM | |
| FBXW4 | VBP1 | 0.984 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | ||
| FBXW4 | PFDN5 | 0.957 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes