hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06625.1
Confidence: Very High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
TAF1D | TATA box-binding protein-associated factor RNA polymerase I subunit D (RNA polymerase I-specific TBP-associated factor 41 kDa) (TAFI41) (TATA box-binding protein-associated factor 1D) (TBP-associated factor 1D) (Transcription initiation factor SL1/TIF-IB subunit D) | 5 | UniProt   NCBI |
TAF1B | TATA box-binding protein-associated factor RNA polymerase I subunit B (RNA polymerase I-specific TBP-associated factor 63 kDa) (TAFI63) (TATA box-binding protein-associated factor 1B) (TBP-associated factor 1B) (Transcription initiation factor SL1/TIF-IB subunit B) | 5 | UniProt   NCBI |
TBP | TATA-box-binding protein (TATA sequence-binding protein) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit) | 5 | UniProt   NCBI |
EPB41L4B | Band 4.1-like protein 4B (Erythrocyte membrane protein band 4.1-like 4B) (FERM-containing protein CG1) (Protein EHM2) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-73863 | 6.29837429836e-06 | 0.75 | TAF1D TAF1B TBP | RNA Polymerase I Transcription Termination |
  REAC:R-HSA-73762 | 2.27017011202e-05 | 0.75 | TAF1D TAF1B TBP | RNA Polymerase I Transcription Initiation |
  CORUM:5727 | 3.07520988333e-05 | 0.5 | TAF1B TBP | TBP-TAF complex |
  REAC:R-HSA-427359 | 3.87912301308e-05 | 0.75 | TAF1D TAF1B TBP | SIRT1 negatively regulates rRNA expression |
  REAC:R-HSA-5250924 | 0.000106339832101 | 0.75 | TAF1D TAF1B TBP | B-WICH complex positively regulates rRNA expression |
  REAC:R-HSA-73772 | 0.000110531761496 | 0.75 | TAF1D TAF1B TBP | RNA Polymerase I Promoter Escape |
  REAC:R-HSA-5250913 | 0.000181248084935 | 0.75 | TAF1D TAF1B TBP | Positive epigenetic regulation of rRNA expression |
  REAC:R-HSA-427413 | 0.000187213642192 | 0.75 | TAF1D TAF1B TBP | NoRC negatively regulates rRNA expression |
  REAC:R-HSA-5250941 | 0.000205891416993 | 0.75 | TAF1D TAF1B TBP | Negative epigenetic regulation of rRNA expression |
  REAC:R-HSA-73854 | 0.000212382296708 | 0.75 | TAF1D TAF1B TBP | RNA Polymerase I Promoter Clearance |
  REAC:R-HSA-73864 | 0.000219007946647 | 0.75 | TAF1D TAF1B TBP | RNA Polymerase I Transcription |
  REAC:R-HSA-212165 | 0.00113904971457 | 0.75 | TAF1D TAF1B TBP | Epigenetic regulation of gene expression |
  CORUM:721 | 0.0249718442456 | 0.25 | TBP | PU.1-TBP complex |
  CORUM:5736 | 0.049938562206 | 0.25 | TBP | Pre-initiation complex (PIC) |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 TAF1D |  TAF1B | 0.998 |            | hein_WMM     bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
 TBP |  TAF1D | 0.993 |            | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
 TAF1D |  EPB41L4B | 0.974 |            | bioplex_WMM     bioplex3_WMM     WMM_only     |
 TAF1B |  EPB41L4B | 0.951 | 0.054           | bioplex_WMM     bioplex3_WMM     WMM_only     |
 TBP |  TAF1B | 0.505 | 0.128           | bioplex_WMM     bioplex3_WMM     WMM_only     |
 TBP |  EPB41L4B | 0.259 | 0.044           | bioplex_WMM     bioplex3_WMM     WMM_only     |
Related Complexes