hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06648.1
Complex Portal: CPX-25496
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DNASE2 | Deoxyribonuclease-2-alpha (EC 3.1.22.1) (Acid DNase) (Deoxyribonuclease II alpha) (DNase II alpha) (Lysosomal DNase II) (R31240_2) | 5 | UniProt NCBI |
| H6PD | GDH/6PGL endoplasmic bifunctional protein [Includes: Hexose-6-phosphate dehydrogenase (Glucose 1-dehydrogenase) (GDH) (EC 1.1.1.47) (Glucose-6-phosphate dehydrogenase) (EC 1.1.1.363); 6-phosphogluconolactonase (6PGL) (EC 3.1.1.31)] | 5 | UniProt NCBI |
| PLA2G15 | Phospholipase A2 group XV (1-O-acylceramide synthase) (ACS) (LCAT-like lysophospholipase) (LLPL) (EC 3.1.1.5) (Lysophospholipase 3) (Lysosomal phospholipase A and acyltransferase) (EC 2.3.1.-, EC 3.1.1.32, EC 3.1.1.4) (Lysosomal phospholipase A2) (LPLA2) | 5 | UniProt NCBI |
| PLBD2 | Putative phospholipase B-like 2 (EC 3.1.1.-) (76 kDa protein) (p76) (LAMA-like protein 2) (Lamina ancestor homolog 2) (Phospholipase B domain-containing protein 2) [Cleaved into: Putative phospholipase B-like 2 32 kDa form; Putative phospholipase B-like 2 45 kDa form] | 5 | UniProt NCBI |
| FBXO6 | F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2) | 5 | UniProt NCBI |
| FBXO44 | F-box only protein 44 (F-box protein FBX30) (F-box/G-domain protein 3) | 5 | UniProt NCBI |
| ENTPD5 | Nucleoside diphosphate phosphatase ENTPD5 (EC 3.6.1.6) (CD39 antigen-like 4) (ER-UDPase) (Ectonucleoside triphosphate diphosphohydrolase 5) (NTPDase 5) (Guanosine-diphosphatase ENTPD5) (GDPase ENTPD5) (Inosine diphosphate phosphatase ENTPD5) (Nucleoside diphosphatase) (Uridine-diphosphatase ENTPD5) (UDPase ENTPD5) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PLA2G15 | FBXO6 | 0.999 | 0.122 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| FBXO6 | H6PD | 0.998 | 0.142 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| FBXO6 | ENTPD5 | 0.995 | 0.092 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| PLBD2 | FBXO6 | 0.981 | 0.236941176471 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| FBXO44 | FBXO6 | 0.974 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ENTPD5 | H6PD | 0.964 | 0.132 |
structurally_consistent (Q9NRD1)
|
bioplex_WMM bioplex3_WMM WMM_only |
| DNASE2 | FBXO6 | 0.963 | 0.144 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| PLA2G15 | H6PD | 0.782 | 0.174 | bioplex_WMM bioplex3_WMM WMM_only | |
| PLA2G15 | ENTPD5 | 0.73 | 0.122 | bioplex_WMM bioplex3_WMM WMM_only | |
| PLA2G15 | PLBD2 | 0.694 | 0.136 | bioplex_WMM bioplex3_WMM WMM_only | |
| FBXO44 | ENTPD5 | 0.675 | bioplex3_WMM WMM_only | ||
| FBXO44 | H6PD | 0.633 | bioplex3_WMM WMM_only | ||
| PLBD2 | H6PD | 0.551 | 0.072 | bioplex_WMM bioplex3_WMM WMM_only | |
| FBXO44 | PLBD2 | 0.525 | bioplex3_WMM WMM_only | ||
| DNASE2 | H6PD | 0.52 | 0.038 | bioplex_WMM bioplex3_WMM WMM_only | |
| FBXO44 | PLA2G15 | 0.401 | bioplex3_WMM WMM_only | ||
| DNASE2 | ENTPD5 | 0.304 | 0.066 | bioplex_WMM bioplex3_WMM WMM_only | |
| PLBD2 | ENTPD5 | 0.302 | 0.036 | bioplex_WMM bioplex3_WMM WMM_only | |
| PLA2G15 | DNASE2 | 0.229 | 0.028 | bioplex_WMM bioplex3_WMM WMM_only | |
| FBXO44 | DNASE2 | 0.066 | bioplex3_WMM WMM_only | ||
| DNASE2 | PLBD2 | 0.066 | 0.052 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes