hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_06652.1

Confidence: Very High

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Genename	Protein Name	Uniprot Annotation Score	Links
ARAP1	Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (Centaurin-delta-2) (Cnt-d2)	5	UniProt NCBI
CAPZA1	F-actin-capping protein subunit alpha-1 (CapZ alpha-1)	5	UniProt NCBI
CAPZA2	F-actin-capping protein subunit alpha-2 (CapZ alpha-2)	5	UniProt NCBI
CAPZB	F-actin-capping protein subunit beta (CapZ beta)	5	UniProt NCBI
CARMIL2	Capping protein, Arp2/3 and myosin-I linker protein 2 (Capping protein regulator and myosin 1 linker 2) (F-actin-uncapping protein RLTPR) (Leucine-rich repeat-containing protein 16C) (RGD, leucine-rich repeat, tropomodulin and proline-rich-containing protein)	5	UniProt NCBI
CPVL	Probable serine carboxypeptidase CPVL (EC 3.4.16.-) (Carboxypeptidase, vitellogenic-like) (Vitellogenic carboxypeptidase-like protein) (VCP-like protein) (hVLP)	4	UniProt NCBI
CRACD	Capping protein-inhibiting regulator of actin dynamics (Cancer-related regulator of actin dynamics)	5	UniProt NCBI
KIAA1671	Uncharacterized protein KIAA1671	2	UniProt NCBI
PLEKHO1	Pleckstrin homology domain-containing family O member 1 (PH domain-containing family O member 1) (C-Jun-binding protein) (JBP) (Casein kinase 2-interacting protein 1) (CK2-interacting protein 1) (CKIP-1) (Osteoclast maturation-associated gene 120 protein)	5	UniProt NCBI
PLEKHO2	Pleckstrin homology domain-containing family O member 2 (PH domain-containing family O member 2) (Pleckstrin homology domain-containing family Q member 1) (PH domain-containing family Q member 1)	3	UniProt NCBI

Showing 1 to 10 of 14 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:6484	3.94753678843e-13	0.357142857143	WASHC4 WASHC2C CAPZB WASHC5 CAPZA1	WASH-CAPZalpa/beta complex
GO:0071203	1.89933032265e-11	0.428571428571	CAPZB WASHC4 WASHC5 RCSD1 WASHC2C CAPZA1	WASH complex
GO:0110053	5.06417153938e-10	0.642857142857	CAPZB CARMIL2 CAPZA2 WASHC5 ARAP1 WASHC4 WASHC2C CAPZA1 CRACD	regulation of actin filament organization
GO:0051693	8.22359366445e-10	0.428571428571	CAPZB CRACD CAPZA2 WASHC2C CAPZA1 CARMIL2	actin filament capping
GO:0051016	8.22359366445e-10	0.428571428571	CAPZB CRACD CAPZA2 WASHC2C CAPZA1 CARMIL2	barbed-end actin filament capping
GO:0030835	1.94918693799e-09	0.428571428571	CAPZB CRACD CAPZA2 WASHC2C CAPZA1 CARMIL2	negative regulation of actin filament depolymerization
GO:0032956	5.12197511213e-09	0.642857142857	CAPZB CARMIL2 CAPZA2 WASHC5 ARAP1 WASHC4 WASHC2C CAPZA1 CRACD	regulation of actin cytoskeleton organization
GO:0030834	9.94091378428e-09	0.428571428571	CAPZB CRACD CAPZA2 WASHC2C CAPZA1 CARMIL2	regulation of actin filament depolymerization
GO:0032970	1.39082153026e-08	0.642857142857	CAPZB CARMIL2 CAPZA2 WASHC5 ARAP1 WASHC4 WASHC2C CAPZA1 CRACD	regulation of actin filament-based process
CORUM:6671	1.9561308074e-08	0.285714285714	WASHC4 CAPZB WASHC5 CAPZA1	PI4K2A-WASH complex

Showing 1 to 10 of 65 entries

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Protein 1	Protein 2	Score	ProteomeHD
CAPZA1	CAPZB	1.0	0.946
CAPZA1	PLEKHO2	1.0	0.078
CAPZB	PLEKHO2	1.0	0.166
CAPZB	PLEKHO1	1.0	0.126
WASHC2C	CAPZA2	1.0	0.094
CAPZB	CAPZA2	1.0	0.934
CAPZA2	WASHC4	1.0	0.226
CAPZA1	PLEKHO1	0.999	0.086
CAPZA2	PLEKHO2	0.999	0.1
CAPZA2	WASHC5	0.999	0.254

Showing 1 to 10 of 81 entries

Related Complexes

Genename	Complexes
WASHC2C	huMAP3_02458.1 huMAP3_06652.1 huMAP3_08077.1 huMAP3_10870.1 huMAP3_12900.1
CRACD	huMAP3_02458.1 huMAP3_06652.1 huMAP3_08077.1 huMAP3_10870.1 huMAP3_12900.1
RCSD1	huMAP3_02458.1 huMAP3_06652.1 huMAP3_08077.1 huMAP3_10870.1 huMAP3_12900.1
WASHC5	huMAP3_05454.1 huMAP3_06652.1 huMAP3_08077.1 huMAP3_10870.1 huMAP3_12900.1
CARMIL2	huMAP3_02458.1 huMAP3_06652.1 huMAP3_08077.1 huMAP3_10870.1 huMAP3_12900.1
PLEKHO2	huMAP3_06652.1 huMAP3_08077.1 huMAP3_10870.1 huMAP3_12900.1
CAPZA1	huMAP3_02458.1 huMAP3_06652.1 huMAP3_08077.1 huMAP3_10870.1 huMAP3_12900.1
ARAP1	huMAP3_00870.1 huMAP3_06652.1 huMAP3_07569.1 huMAP3_08077.1 huMAP3_08747.1 huMAP3_09119.1 huMAP3_10500.1 huMAP3_10870.1 huMAP3_12900.1 huMAP3_15054.1
CAPZB	huMAP3_02458.1 huMAP3_06652.1 huMAP3_08077.1 huMAP3_10870.1 huMAP3_12900.1
KIAA1671	huMAP3_02458.1 huMAP3_06652.1 huMAP3_08077.1 huMAP3_10870.1 huMAP3_12900.1
CPVL	huMAP3_02458.1 huMAP3_02470.1 huMAP3_04946.1 huMAP3_06652.1 huMAP3_08077.1 huMAP3_09952.1 huMAP3_10870.1 huMAP3_11730.1 huMAP3_12900.1
CAPZA2	huMAP3_02458.1 huMAP3_06652.1 huMAP3_08077.1 huMAP3_09348.1 huMAP3_10870.1 huMAP3_12900.1
WASHC4	huMAP3_05454.1 huMAP3_06652.1 huMAP3_08077.1 huMAP3_10870.1 huMAP3_12900.1
PLEKHO1	huMAP3_02458.1 huMAP3_06652.1 huMAP3_08077.1 huMAP3_10870.1 huMAP3_12723.1 huMAP3_12900.1