hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06653.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IQCB1 | IQ calmodulin-binding motif-containing protein 1 (Nephrocystin-5) (p53 and DNA damage-regulated IQ motif protein) (PIQ) | 5 | UniProt NCBI |
| CEP97 | Centrosomal protein of 97 kDa (Cep97) (Leucine-rich repeat and IQ domain-containing protein 2) | 5 | UniProt NCBI |
| CCP110 | Centriolar coiled-coil protein of 110 kDa (Centrosomal protein of 110 kDa) (CP110) (Cep110) | 5 | UniProt NCBI |
| KIF24 | Kinesin-like protein KIF24 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5620912 | 2.8038653175e-07 | 1.0 | IQCB1 KIF24 CEP97 CCP110 | Anchoring of the basal body to the plasma membrane |
| REAC:R-HSA-5617833 | 4.94511818238e-06 | 1.0 | IQCB1 KIF24 CEP97 CCP110 | Cilium Assembly |
| REAC:R-HSA-1852241 | 2.23881020941e-05 | 1.0 | IQCB1 KIF24 CEP97 CCP110 | Organelle biogenesis and maintenance |
| GO:1902018 | 0.000313494264121 | 0.75 | KIF24 CEP97 CCP110 | negative regulation of cilium assembly |
| GO:0120033 | 0.00155882617412 | 0.75 | KIF24 CEP97 CCP110 | negative regulation of plasma membrane bounded cell projection assembly |
| GO:1902116 | 0.00323764786551 | 0.75 | KIF24 CEP97 CCP110 | negative regulation of organelle assembly |
| GO:0060271 | 0.00604511321054 | 1.0 | IQCB1 KIF24 CEP97 CCP110 | cilium assembly |
| REAC:R-HSA-9013424 | 0.006081926491 | 0.5 | CEP97 CCP110 | RHOV GTPase cycle |
| WP:WP4656 | 0.0063063631888 | 0.5 | CEP97 CCP110 | Joubert syndrome |
| GO:0044782 | 0.00802497752911 | 1.0 | IQCB1 KIF24 CEP97 CCP110 | cilium organization |
| GO:1902017 | 0.0112187083505 | 0.75 | KIF24 CEP97 CCP110 | regulation of cilium assembly |
| GO:0120031 | 0.0282069641472 | 1.0 | IQCB1 KIF24 CEP97 CCP110 | plasma membrane bounded cell projection assembly |
| GO:0030031 | 0.0311314419202 | 1.0 | IQCB1 KIF24 CEP97 CCP110 | cell projection assembly |
| CORUM:6594 | 0.049938562206 | 0.25 | CCP110 | CCP110-CEP290 complex |
| CORUM:6597 | 0.049938562206 | 0.25 | IQCB1 | CEP290-IQCB1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CCP110 | CEP97 | 0.996 | 0.234602739726 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM hein () gupta_WMM gupta () boldt_WMM |
| CCP110 | IQCB1 | 0.995 | 0.256 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| KIF24 | CEP97 | 0.992 | hein_WMM bioplex3_HEK293 bioplex3_WMM hein () boldt_WMM | |
| IQCB1 | CEP97 | 0.99 | 0.188 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only |
| CCP110 | KIF24 | 0.921 | hein_WMM bioplex3_HEK293 bioplex3_WMM boldt_WMM WMM_only |
Related Complexes