hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_06668.1
Confidence: Very High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FADD | FAS-associated death domain protein (FAS-associating death domain-containing protein) (Growth-inhibiting gene 3 protein) (Mediator of receptor induced toxicity) | 5 | UniProt NCBI |
| NTF4 | Neurotrophin-4 (NT-4) (Neurotrophin-5) (NT-5) (Neutrophic factor 4) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5861 | 0.0249718442455 | 1.0 | FADD | FAS-FADD-CASP10 complex |
| KEGG:04215 | 0.0465789376469 | 1.0 | FADD | Apoptosis - multiple species |
| CORUM:5473 | 0.0499436884912 | 1.0 | FADD | DISC complex (FAS, FADD, CASP8) |
| CORUM:5800 | 0.0499436884912 | 1.0 | FADD | DISC complex (FAS, FADD, CASP8) |
| CORUM:5808 | 0.0499436884912 | 1.0 | FADD | DISC complex (CD95, FADD, CASP8) |
| CORUM:5856 | 0.0499436884912 | 1.0 | FADD | AK2-FADD-caspase-10 (AFAC10) complex |
| CORUM:5859 | 0.0499436884912 | 1.0 | FADD | FAS-FADD-CASP8-CASP10 complex |
| CORUM:5860 | 0.0499436884912 | 1.0 | FADD | DISC complex (FAS, FADD, CASP8) |
| CORUM:5991 | 0.0499436884912 | 1.0 | FADD | LRRK2-FADD-CASP8 complex |
| CORUM:6175 | 0.0499436884912 | 1.0 | FADD | Caspase-10-SUMO-FADD/Drp1 complex |
| REAC:R-HSA-75157 | 0.0499436884912 | 1.0 | FADD | FasL/ CD95L signaling |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| FADD | NTF4 | 0.98 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes